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  1. ALA4514410

    Name:
    methyl 4-(5-chloro-2-((1S)-1-(6-(3-chlorophenyl)-2
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    Mol. Formula:
    C29H26Cl2N4O4

    M.W.:
    565.46

    Type:
    Unknown

    AlogP:
    7.43

    Polar Surface Area:
    96.55

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  2. ALA4476061

    Name:
    Methyl N-[(10R,14S)-14-[1-(3-Chloro-2-fluorophenyl
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    Mol. Formula:
    C32H29ClF4N6O6

    M.W.:
    705.07

    Type:
    Unknown

    AlogP:
    6.13

    Polar Surface Area:
    127.24

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  3. ALA4522419

    Name:
    Methyl N-[(10R,14S)-14-[1-(3-Chlorophenyl)-5-oxopy
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    Mol. Formula:
    C31H32ClN5O5

    M.W.:
    590.08

    Type:
    Unknown

    AlogP:
    5.55

    Polar Surface Area:
    129.73

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  4. ALA4535183

    Name:
    (S)-methyl 4-(5-chloro-2-(1-(3-(3-chlorobenzyl)ure
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    Mol. Formula:
    C27H25Cl2N5O3

    M.W.:
    538.44

    Type:
    Unknown

    AlogP:
    6.35

    Polar Surface Area:
    108.14

    HBA:
    4

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
  5. ALA4534617

    Name:
    Methyl N-[(10R,14S)-14-[1-(3-Chloro-2-fluorophenyl
    Show More

    Mol. Formula:
    C31H31Cl2FN6O4

    M.W.:
    641.53

    Type:
    Unknown

    AlogP:
    6.44

    Polar Surface Area:
    127.24

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.25

    DETAILS
  6. ALA4554665

    Name:
    Methyl N-[(10R,14S)-14-[1-(3-Chlorophenyl)-1H-pyra
    Show More

    Mol. Formula:
    C30H29ClN6O4

    M.W.:
    573.05

    Type:
    Unknown

    AlogP:
    6.00

    Polar Surface Area:
    127.24

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  7. ALA4552656

    Name:
    Methyl N-[(10R,14S)-14-[3-(3-Chloro-2-fluorophenyl
    Show More

    Mol. Formula:
    C31H29ClFN5O5

    M.W.:
    606.05

    Type:
    Unknown

    AlogP:
    6.91

    Polar Surface Area:
    135.45

    HBA:
    7

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.23

    DETAILS
  8. ALA4552540

    Name:
    {(S)-15-[(S)-6-(3-Chlorophenyl)-2-oxo-[1,3]oxazina
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    Mol. Formula:
    C28H28ClN5O5

    M.W.:
    550.02

    Type:
    Unknown

    AlogP:
    6.21

    Polar Surface Area:
    125.65

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  9. ALA4530525

    Name:
    Methyl N-[(10R,14S)-14-[1-(3-chloro-2-fluorophenyl
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    Mol. Formula:
    C29H29ClFN7O4

    M.W.:
    594.05

    Type:
    Unknown

    AlogP:
    5.77

    Polar Surface Area:
    143.03

    HBA:
    7

    HBD:
    4

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  10. ALA4515523

    Name:
    {(S)-15-[(R)-6-(3-Chlorophenyl)-2-oxo-[1,3]oxazina
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    Mol. Formula:
    C28H28ClN5O5

    M.W.:
    550.02

    Type:
    Unknown

    AlogP:
    6.21

    Polar Surface Area:
    125.65

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  11. ALA4585824

    Name:
    Methyl N-[(10R,14S)-14-(2,6-Difluoro-4-methylbenza
    Show More

    Mol. Formula:
    C28H28F2N4O4

    M.W.:
    522.55

    Type:
    Unknown

    AlogP:
    5.74

    Polar Surface Area:
    109.42

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  12. ALA4861304

    Name:
    (S)-4-(2-(2-(3-chloro-2-fluorophenyl)-4-methyl-1H-
    Show More

    Mol. Formula:
    C27H22ClFN4O4

    M.W.:
    520.95

    Type:
    Unknown

    AlogP:
    4.86

    Polar Surface Area:
    124.18

    HBA:
    4

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  13. ALA4860514

    Name:
    (S)-4-(2-(2-(3-cyanophenyl)-1-hydroxy-4-methyl-1H-
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    Mol. Formula:
    C28H23N5O5

    M.W.:
    509.52

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    157.34

    HBA:
    7

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  14. ALA4856757

    Name:
    (S)-4-(2-(1-hydroxy-4-methyl-2-phenyl-1H-imidazole
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    Mol. Formula:
    C27H24N4O5

    M.W.:
    484.51

    Type:
    Unknown

    AlogP:
    3.77

    Polar Surface Area:
    133.55

    HBA:
    6

    HBD:
    4

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  15. ALA4856139

    Name:
    5-((2S)-2-(2-(3-chloro-2-fluorophenyl)-1-hydroxy-4
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    Mol. Formula:
    C33H28ClFN6O6

    M.W.:
    659.07

    Type:
    Unknown

    AlogP:
    5.40

    Polar Surface Area:
    178.44

    HBA:
    7

    HBD:
    6

    #RO5 Violations:
    3

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.11

    DETAILS
  16. ALA4879256

    Name:
    5-((2S)-2-(2-(3-chloro-2-fluorophenyl)-1-hydroxy-4
    Show More

    Mol. Formula:
    C29H22ClF2N5O5

    M.W.:
    593.97

    Type:
    Unknown

    AlogP:
    5.19

    Polar Surface Area:
    149.34

    HBA:
    6

    HBD:
    5

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  17. ALA4878154

    Name:
    4-((2S)-2-(2-(3-chloro-2-fluorophenyl)-1-methoxy-4
    Show More

    Mol. Formula:
    C28H24ClFN4O5

    M.W.:
    550.97

    Type:
    Unknown

    AlogP:
    4.39

    Polar Surface Area:
    122.55

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  18. ALA4876276

    Name:
    (S)-4-(2-(2-(4-cyanophenyl)-1-hydroxy-4-methyl-1H-
    Show More

    Mol. Formula:
    C28H23N5O5

    M.W.:
    509.52

    Type:
    Unknown

    AlogP:
    3.65

    Polar Surface Area:
    157.34

    HBA:
    7

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  19. ALA4875072

    Name:
    5-((2S)-2-(2-(3-chloro-2-fluorophenyl)-1-hydroxy-4
    Show More

    Mol. Formula:
    C36H34ClFN6O6

    M.W.:
    701.15

    Type:
    Unknown

    AlogP:
    6.57

    Polar Surface Area:
    178.44

    HBA:
    7

    HBD:
    6

    #RO5 Violations:
    3

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.09

    DETAILS
  20. ALA4874449

    Name:
    4-((2S)-2-(2-(3-chloro-2-fluorophenyl)-1-hydroxy-4
    Show More

    Mol. Formula:
    C27H22ClFN4O5

    M.W.:
    536.95

    Type:
    Unknown

    AlogP:
    4.57

    Polar Surface Area:
    133.55

    HBA:
    6

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
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