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  1. ALA4217694

    Name:
    4-(1-ethyl-5-fluoro-2,3-dihydro-1H-benzo[d]pyrrolo
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    Mol. Formula:
    C27H30F2N8

    M.W.:
    504.59

    Type:
    Small molecule

    AlogP:
    4.55

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  2. ALA4215126

    Name:
    N-(5-((4-ethylpiperazin-1-yl)methyl)-6-methylpyrid
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    Mol. Formula:
    C28H32F2N8

    M.W.:
    518.62

    Type:
    Small molecule

    AlogP:
    4.86

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  3. ALA4213847

    Name:
    4-(1-Ethyl-5-fluoro-2,3-dihydro-1H-benzo[d]pyrrolo
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    Mol. Formula:
    C28H32F2N8

    M.W.:
    518.62

    Type:
    Small molecule

    AlogP:
    4.94

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  4. ALA4212542

    Name:
    N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-
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    Mol. Formula:
    C27H30F2N8

    M.W.:
    504.59

    Type:
    Small molecule

    AlogP:
    4.55

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  5. ALA4211828

    Name:
    5-Fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-benzo
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    Mol. Formula:
    C28H32F2N8

    M.W.:
    518.62

    Type:
    Small molecule

    AlogP:
    4.94

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  6. ALA4209318

    Name:
    5-Fluoro-4-(5-fluoro-1-methyl-2,3-dihydro-1H-benzo
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    Mol. Formula:
    C26H28F2N8

    M.W.:
    490.56

    Type:
    Small molecule

    AlogP:
    4.16

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  7. ALA4207966

    Name:
    N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-
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    Mol. Formula:
    C27H31FN8

    M.W.:
    486.60

    Type:
    Small molecule

    AlogP:
    4.42

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  8. ALA4207804

    Name:
    N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-
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    Mol. Formula:
    C28H32F2N8

    M.W.:
    518.62

    Type:
    Small molecule

    AlogP:
    4.63

    Polar Surface Area:
    75.00

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
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