Type:
Small molecule

AlogP:
7.37

Polar Surface Area:
208.95

HBA:
15

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.06

Type:
Small molecule

AlogP:
7.40

Polar Surface Area:
208.95

HBA:
15

HBD:
3

#RO5 Violations:
3

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.07

Type:
Small molecule

AlogP:
6.82

Polar Surface Area:
69.04

HBA:
5

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.18

Type:
Small molecule

AlogP:
6.38

Polar Surface Area:
69.04

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.27

Type:
Small molecule

AlogP:
4.12

Polar Surface Area:
80.04

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

Type:
Small molecule

AlogP:
4.34

Polar Surface Area:
86.11

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.47

Type:
Small molecule

AlogP:
3.20

Polar Surface Area:
78.27

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.47

Type:
Small molecule

AlogP:
4.22

Polar Surface Area:
78.27

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.58

Type:
Small molecule

AlogP:
3.79

Polar Surface Area:
89.27

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.54

Type:
Small molecule

AlogP:
5.05

Polar Surface Area:
65.38

HBA:
5

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.38

Type:
Small molecule

AlogP:
4.48

Polar Surface Area:
81.07

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.39

Type:
Small molecule

AlogP:
4.46

Polar Surface Area:
87.50

HBA:
7

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.31

Type:
Small molecule

AlogP:
4.83

Polar Surface Area:
78.27

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.36

Type:
Small molecule

AlogP:
4.44

Polar Surface Area:
78.27

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.40

Type:
Small molecule

AlogP:
4.98

Polar Surface Area:
69.04

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.42

Type:
Small molecule

AlogP:
6.53

Polar Surface Area:
73.97

HBA:
6

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.22

Type:
Small molecule

AlogP:
5.16

Polar Surface Area:
69.04

HBA:
6

HBD:
1

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.36

Type:
Small molecule

AlogP:
4.83

Polar Surface Area:
78.27

HBA:
6

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.36

Type:
Small molecule

AlogP:
3.15

Polar Surface Area:
109.50

HBA:
7

HBD:
3

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.44

Type:
Small molecule

AlogP:
5.89

Polar Surface Area:
87.50

HBA:
7

HBD:
1

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.17