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  1. ALA4873486

    Name:
    4-((E)-7'-Methoxy-2,2,2',2'-tetramethyl-2,3,2',3'-
    Show More

    Mol. Formula:
    C31H39NO5

    M.W.:
    505.66

    Type:
    Unknown

    AlogP:
    6.51

    Polar Surface Area:
    57.23

    HBA:
    5

    HBD:
    ---

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  2. ALA5287420

    Name:
    2-Amino-8-ethyl-4-(5-methoxy-2-methyl-1H-indol-3-y
    Show More

    Mol. Formula:
    C31H27N5O3

    M.W.:
    517.59

    Type:
    ---

    AlogP:
    5.18

    Polar Surface Area:
    118.95

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  3. ALA5286911

    Name:
    2-Amino-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-y
    Show More

    Mol. Formula:
    C32H29N5O2

    M.W.:
    515.62

    Type:
    ---

    AlogP:
    6.21

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  4. ALA5286541

    Name:
    3-ethyl-2-methyl-3,4-dihydroquinazolin-4-one

    Mol. Formula:
    C11H12N2O

    M.W.:
    188.23

    Type:
    ---

    AlogP:
    1.72

    Polar Surface Area:
    34.89

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    1

    Passes Ro3:
    Y

    QED Weighted:
    0.68

    DETAILS
  5. ALA5285667

    Name:
    2-Amino-8-(tert-butyl)-4-(2-methyl-1H-indol-3-yl)-
    Show More

    Mol. Formula:
    C31H27N5O2

    M.W.:
    501.59

    Type:
    ---

    AlogP:
    5.90

    Polar Surface Area:
    120.58

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  6. ALA5284562

    Name:
    2-Amino-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-y
    Show More

    Mol. Formula:
    C30H25N5O2

    M.W.:
    487.56

    Type:
    ---

    AlogP:
    5.40

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  7. ALA5284498

    Name:
    2-Amino-4-(2-methyl-1H-indol-3-yl)-6-(3-methyl-4-o
    Show More

    Mol. Formula:
    C31H27N5O2

    M.W.:
    501.59

    Type:
    ---

    AlogP:
    5.56

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  8. ALA5281368

    Name:
    2-Amino-8-(tert-butyl)-4-(5-chloro-2-methyl-1H-ind
    Show More

    Mol. Formula:
    C32H28ClN5O2

    M.W.:
    550.06

    Type:
    ---

    AlogP:
    6.56

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  9. ALA5280861

    Name:
    2-Amino-8-(tert-butyl)-4-(5-methoxy-2-methyl-1H-in
    Show More

    Mol. Formula:
    C33H31N5O3

    M.W.:
    545.64

    Type:
    ---

    AlogP:
    5.91

    Polar Surface Area:
    118.95

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.29

    DETAILS
  10. ALA5280166

    Name:
    2-Amino-4-(5-methoxy-2-methyl-1H-indol-3-yl)-8-met
    Show More

    Mol. Formula:
    C30H25N5O3

    M.W.:
    503.56

    Type:
    ---

    AlogP:
    4.93

    Polar Surface Area:
    118.95

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  11. ALA5279547

    Name:
    2-amino-6-(3-ethyl-4-oxo-3,4-dihydroquinazolin-2-y
    Show More

    Mol. Formula:
    C21H18N4O2

    M.W.:
    358.40

    Type:
    ---

    AlogP:
    3.02

    Polar Surface Area:
    93.93

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.76

    DETAILS
  12. ALA5279507

    Name:
    2-amino-4H-chromene-3-carbonitrile

    Mol. Formula:
    C10H8N2O

    M.W.:
    172.19

    Type:
    ---

    AlogP:
    1.27

    Polar Surface Area:
    59.04

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    ---

    Passes Ro3:
    Y

    QED Weighted:
    0.64

    DETAILS
  13. ALA5279224

    Name:
    2-Amino-8-ethyl-4-(2-methyl-1H-indol-3-yl)-6-(3-me
    Show More

    Mol. Formula:
    C30H25N5O2

    M.W.:
    487.56

    Type:
    ---

    AlogP:
    5.17

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  14. ALA5278983

    Name:
    2-Amino-8-ethyl-4-(2-methyl-1H-indol-3-yl)-6-(4-ox
    Show More

    Mol. Formula:
    C29H23N5O2

    M.W.:
    473.54

    Type:
    ---

    AlogP:
    5.16

    Polar Surface Area:
    120.58

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  15. ALA5278352

    Name:
    2-Amino-4-(5-methoxy-2-methyl-1H-indol-3-yl-6-(3-m
    Show More

    Mol. Formula:
    C32H29N5O3

    M.W.:
    531.62

    Type:
    ---

    AlogP:
    5.57

    Polar Surface Area:
    118.95

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.31

    DETAILS
  16. ALA4866403

    Name:
    4-((E)-7'-Methoxy-2,2,2',2'-tetramethyl-2,3,2',3'-
    Show More

    Mol. Formula:
    C32H42N2O5

    M.W.:
    534.70

    Type:
    Unknown

    AlogP:
    5.66

    Polar Surface Area:
    60.47

    HBA:
    6

    HBD:
    ---

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  17. ALA4863210

    Name:
    {6-[6-((E)-7'-Methoxy-2,2,2',2'-tetramethyl-2,3,2'
    Show More

    Mol. Formula:
    C38H54N2O7

    M.W.:
    650.86

    Type:
    Unknown

    AlogP:
    8.09

    Polar Surface Area:
    104.35

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    13

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
  18. ALA5291244

    Name:
    2-Amino-4-(5-chloro-2-methyl-1H-indol-3-yl)-8-meth
    Show More

    Mol. Formula:
    C29H22ClN5O2

    M.W.:
    507.98

    Type:
    ---

    AlogP:
    5.57

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.32

    DETAILS
  19. ALA5288900

    Name:
    2-Amino-4-(5-chloro-2-methyl-1H-indol-3-yl)-8-isop
    Show More

    Mol. Formula:
    C31H26ClN5O2

    M.W.:
    536.04

    Type:
    ---

    AlogP:
    6.39

    Polar Surface Area:
    109.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  20. ALA4857873

    Name:
    5-((E)-7'-Methoxy-2,2,2',2'-tetramethyl-2,3,2',3'-
    Show More

    Mol. Formula:
    C33H46N2O5

    M.W.:
    550.74

    Type:
    Unknown

    AlogP:
    6.39

    Polar Surface Area:
    78.05

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    12

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
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