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13 Items

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  1. ALA4483580

    Name:
    5'-(Cyclopropylmethoxy)-6'-(4-(isoindolin-2-yl)but
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    Mol. Formula:
    C28H35N3O2

    M.W.:
    445.61

    Type:
    Unknown

    AlogP:
    5.46

    Polar Surface Area:
    60.08

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  2. ALA4476514

    Name:
    (2-(4-(pyrrolidin-1-ylmethoxy)phenylamino)-1,4-phe
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    Mol. Formula:
    C41H60N6O3

    M.W.:
    684.97

    Type:
    Unknown

    AlogP:
    6.54

    Polar Surface Area:
    71.60

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    13

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  3. ALA4476309

    Name:
    5'-(Cyclopropylmethoxy)-6'-(3-(isoindolin-2-yl)pro
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    Mol. Formula:
    C27H33N3O2

    M.W.:
    431.58

    Type:
    Unknown

    AlogP:
    5.07

    Polar Surface Area:
    60.08

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  4. Type:
    Unknown

    AlogP:
    2.40

    Polar Surface Area:
    73.74

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  5. ALA4570122

    Name:
    3-(4-(2-((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,
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    Mol. Formula:
    C43H60N8O4

    M.W.:
    753.00

    Type:
    Unknown

    AlogP:
    5.87

    Polar Surface Area:
    123.57

    HBA:
    11

    HBD:
    1

    #RO5 Violations:
    3

    #Rotatable Bonds:
    18

    Passes Ro3:
    N

    QED Weighted:
    0.16

    DETAILS
  6. ALA4528213

    Name:
    5-(Cyclopropylmethoxy)-6-(3-(isoindolin-2-yl)propo
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    Mol. Formula:
    C25H31N3O2

    M.W.:
    405.54

    Type:
    Unknown

    AlogP:
    4.54

    Polar Surface Area:
    60.08

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.66

    DETAILS
  7. ALA4573889

    Name:
    3-(4-(((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,3-
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    Mol. Formula:
    C42H58N8O4

    M.W.:
    738.98

    Type:
    Unknown

    AlogP:
    5.83

    Polar Surface Area:
    123.57

    HBA:
    11

    HBD:
    1

    #RO5 Violations:
    3

    #Rotatable Bonds:
    17

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  8. ALA4577068

    Name:
    2-(4-(((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,3-
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    Mol. Formula:
    C41H56N8O4

    M.W.:
    724.95

    Type:
    Unknown

    AlogP:
    5.44

    Polar Surface Area:
    123.57

    HBA:
    11

    HBD:
    1

    #RO5 Violations:
    3

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.19

    DETAILS
  9. ALA4588285

    Name:
    [3-(aminomethyl)-4-methoxy-5-(3-pyrrolidin-1-ylpro
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    Mol. Formula:
    C16H27N3O2

    M.W.:
    293.41

    Type:
    Unknown

    AlogP:
    1.48

    Polar Surface Area:
    73.74

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.71

    DETAILS
  10. ALA4457929

    Name:
    5-(Cyclopropylmethoxy)-6-(4-(isoindolin-2-yl)butox
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    Mol. Formula:
    C26H33N3O2

    M.W.:
    419.57

    Type:
    Unknown

    AlogP:
    4.93

    Polar Surface Area:
    60.08

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.59

    DETAILS
  11. ALA4452624

    Name:
    2-(4-(((2-(4-((2-Amino-5-(cyclopropylmethoxy)-3,3-
    Show More

    Mol. Formula:
    C42H58N8O4

    M.W.:
    738.98

    Type:
    Unknown

    AlogP:
    5.83

    Polar Surface Area:
    123.57

    HBA:
    11

    HBD:
    1

    #RO5 Violations:
    3

    #Rotatable Bonds:
    17

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  12. ALA4451634

    Name:
    2-(4-(2-((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,
    Show More

    Mol. Formula:
    C42H58N8O4

    M.W.:
    738.98

    Type:
    Unknown

    AlogP:
    5.48

    Polar Surface Area:
    123.57

    HBA:
    11

    HBD:
    1

    #RO5 Violations:
    3

    #Rotatable Bonds:
    17

    Passes Ro3:
    N

    QED Weighted:
    0.18

    DETAILS
  13. ALA4450765

    Name:
    3-(aminomethyl)-5-(3-isoindolin-2-ylpropoxy)-4-met
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    Mol. Formula:
    C20H25N3O3

    M.W.:
    355.44

    Type:
    Unknown

    AlogP:
    2.04

    Polar Surface Area:
    90.81

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.71

    DETAILS
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