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ALA4483580 Name:
5'-(Cyclopropylmethoxy)-6'-(4-(isoindolin-2-yl)but
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Mol. Formula:
C28H35N3O2
M.W.:
445.61
Type:
Unknown
AlogP:
5.46
Polar Surface Area:
60.08
HBA:
5
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.52
DETAILS
CLOSE
ALA4476514 Name:
(2-(4-(pyrrolidin-1-ylmethoxy)phenylamino)-1,4-phe
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Mol. Formula:
C41H60N6O3
M.W.:
684.97
Type:
Unknown
AlogP:
6.54
Polar Surface Area:
71.60
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
13
Passes Ro3:
N
QED Weighted:
0.26
DETAILS
CLOSE
ALA4476309 Name:
5'-(Cyclopropylmethoxy)-6'-(3-(isoindolin-2-yl)pro
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Mol. Formula:
C27H33N3O2
M.W.:
431.58
Type:
Unknown
AlogP:
5.07
Polar Surface Area:
60.08
HBA:
5
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.59
DETAILS
CLOSE
Type:
Unknown
AlogP:
2.40
Polar Surface Area:
73.74
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.72
DETAILS
CLOSE
ALA4570122 Name:
3-(4-(2-((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,
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Mol. Formula:
C43H60N8O4
M.W.:
753.00
Type:
Unknown
AlogP:
5.87
Polar Surface Area:
123.57
HBA:
11
HBD:
1
#RO5 Violations:
3
#Rotatable Bonds:
18
Passes Ro3:
N
QED Weighted:
0.16
DETAILS
CLOSE
ALA4528213 Name:
5-(Cyclopropylmethoxy)-6-(3-(isoindolin-2-yl)propo
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Mol. Formula:
C25H31N3O2
M.W.:
405.54
Type:
Unknown
AlogP:
4.54
Polar Surface Area:
60.08
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.66
DETAILS
CLOSE
ALA4573889 Name:
3-(4-(((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,3-
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Mol. Formula:
C42H58N8O4
M.W.:
738.98
Type:
Unknown
AlogP:
5.83
Polar Surface Area:
123.57
HBA:
11
HBD:
1
#RO5 Violations:
3
#Rotatable Bonds:
17
Passes Ro3:
N
QED Weighted:
0.17
DETAILS
CLOSE
ALA4577068 Name:
2-(4-(((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,3-
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Mol. Formula:
C41H56N8O4
M.W.:
724.95
Type:
Unknown
AlogP:
5.44
Polar Surface Area:
123.57
HBA:
11
HBD:
1
#RO5 Violations:
3
#Rotatable Bonds:
16
Passes Ro3:
N
QED Weighted:
0.19
DETAILS
CLOSE
ALA4588285 Name:
[3-(aminomethyl)-4-methoxy-5-(3-pyrrolidin-1-ylpro
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Mol. Formula:
C16H27N3O2
M.W.:
293.41
Type:
Unknown
AlogP:
1.48
Polar Surface Area:
73.74
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.71
DETAILS
CLOSE
ALA4457929 Name:
5-(Cyclopropylmethoxy)-6-(4-(isoindolin-2-yl)butox
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Mol. Formula:
C26H33N3O2
M.W.:
419.57
Type:
Unknown
AlogP:
4.93
Polar Surface Area:
60.08
HBA:
5
HBD:
1
#RO5 Violations:
---
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.59
DETAILS
CLOSE
ALA4452624 Name:
2-(4-(((2-(4-((2-Amino-5-(cyclopropylmethoxy)-3,3-
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Mol. Formula:
C42H58N8O4
M.W.:
738.98
Type:
Unknown
AlogP:
5.83
Polar Surface Area:
123.57
HBA:
11
HBD:
1
#RO5 Violations:
3
#Rotatable Bonds:
17
Passes Ro3:
N
QED Weighted:
0.17
DETAILS
CLOSE
ALA4451634 Name:
2-(4-(2-((2-(3-((2-Amino-5-(cyclopropylmethoxy)-3,
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Mol. Formula:
C42H58N8O4
M.W.:
738.98
Type:
Unknown
AlogP:
5.48
Polar Surface Area:
123.57
HBA:
11
HBD:
1
#RO5 Violations:
3
#Rotatable Bonds:
17
Passes Ro3:
N
QED Weighted:
0.18
DETAILS
CLOSE
ALA4450765 Name:
3-(aminomethyl)-5-(3-isoindolin-2-ylpropoxy)-4-met
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Mol. Formula:
C20H25N3O3
M.W.:
355.44
Type:
Unknown
AlogP:
2.04
Polar Surface Area:
90.81
HBA:
5
HBD:
2
#RO5 Violations:
---
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.71
DETAILS
CLOSE
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