Type:
Small molecule

AlogP:
-1.38

Polar Surface Area:
406.55

HBA:
12

HBD:
13

#RO5 Violations:
3

#Rotatable Bonds:
24

Passes Ro3:
N

QED Weighted:
0.02

Type:
Small molecule

AlogP:
-2.22

Polar Surface Area:
393.85

HBA:
11

HBD:
14

#RO5 Violations:
3

#Rotatable Bonds:
22

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
-0.97

Polar Surface Area:
285.54

HBA:
10

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.12

Type:
Small molecule

AlogP:
-0.65

Polar Surface Area:
282.75

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.11

Type:
Small molecule

AlogP:
-1.25

Polar Surface Area:
307.35

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
17

Passes Ro3:
N

QED Weighted:
0.04

Type:
Small molecule

AlogP:
-0.65

Polar Surface Area:
282.75

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.11

Type:
Small molecule

AlogP:
-2.76

Polar Surface Area:
375.76

HBA:
13

HBD:
11

#RO5 Violations:
3

#Rotatable Bonds:
22

Passes Ro3:
N

QED Weighted:
0.05

Type:
Small molecule

AlogP:
-0.37

Polar Surface Area:
279.75

HBA:
10

HBD:
6

#RO5 Violations:
2

#Rotatable Bonds:
15

Passes Ro3:
N

QED Weighted:
0.13

Type:
Small molecule

AlogP:
-1.85

Polar Surface Area:
294.33

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.09

Type:
Small molecule

AlogP:
-0.74

Polar Surface Area:
322.84

HBA:
11

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.09

Type:
Small molecule

AlogP:
-1.34

Polar Surface Area:
328.63

HBA:
11

HBD:
7

#RO5 Violations:
3

#Rotatable Bonds:
18

Passes Ro3:
N

QED Weighted:
0.09

Type:
Small molecule

AlogP:
-1.25

Polar Surface Area:
288.54

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.10

Type:
Small molecule

AlogP:
-1.61

Polar Surface Area:
331.63

HBA:
11

HBD:
8

#RO5 Violations:
3

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.07

Type:
Small molecule

AlogP:
-1.61

Polar Surface Area:
331.63

HBA:
11

HBD:
8

#RO5 Violations:
3

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.07

Type:
Small molecule

AlogP:
-1.85

Polar Surface Area:
294.33

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.09

Type:
Small molecule

AlogP:
-2.21

Polar Surface Area:
337.42

HBA:
11

HBD:
8

#RO5 Violations:
3

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.07

Type:
Small molecule

AlogP:
-1.25

Polar Surface Area:
288.54

HBA:
10

HBD:
7

#RO5 Violations:
2

#Rotatable Bonds:
16

Passes Ro3:
N

QED Weighted:
0.10

Type:
Small molecule

AlogP:
-0.41

Polar Surface Area:
320.05

HBA:
11

HBD:
8

#RO5 Violations:
3

#Rotatable Bonds:
19

Passes Ro3:
N

QED Weighted:
0.08

Type:
Small molecule

AlogP:
-1.01

Polar Surface Area:
344.65

HBA:
11

HBD:
10

#RO5 Violations:
3

#Rotatable Bonds:
20

Passes Ro3:
N

QED Weighted:
0.03

Type:
Small molecule

AlogP:
-1.25

Polar Surface Area:
307.35

HBA:
10

HBD:
9

#RO5 Violations:
2

#Rotatable Bonds:
17

Passes Ro3:
N

QED Weighted:
0.04