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  1. ALA4878471

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C23H22N6O2

    M.W.:
    414.47

    Type:
    Unknown

    AlogP:
    4.20

    Polar Surface Area:
    92.27

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  2. ALA4878431

    Name:
    1-(4-(7-(dimethylamino)quinazolin-4-yloxy)phenyl)-
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    Mol. Formula:
    C24H20F3N5O2

    M.W.:
    467.45

    Type:
    Unknown

    AlogP:
    6.15

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  3. ALA4878293

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C22H23N7O2

    M.W.:
    417.47

    Type:
    Unknown

    AlogP:
    3.54

    Polar Surface Area:
    97.20

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  4. ALA4877828

    Name:
    1-(4-((7-(Methylamino)quinazolin-4-yl)oxy)phenyl)-
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    Mol. Formula:
    C22H19N5O2

    M.W.:
    385.43

    Type:
    Unknown

    AlogP:
    5.11

    Polar Surface Area:
    88.17

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  5. ALA4877440

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C24H23N5O3

    M.W.:
    429.48

    Type:
    Unknown

    AlogP:
    5.14

    Polar Surface Area:
    88.61

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  6. ALA4877247

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C23H21N5O2

    M.W.:
    399.45

    Type:
    Unknown

    AlogP:
    5.13

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  7. ALA4877148

    Name:
    1-(3-Chloro-4-methoxyphenyl)-3-(4-((7-(dimethylami
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    Mol. Formula:
    C24H22ClN5O3

    M.W.:
    463.93

    Type:
    Unknown

    AlogP:
    5.79

    Polar Surface Area:
    88.61

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  8. ALA4877038

    Name:
    1-(4-((7-Methoxyquinazolin-4-yl)amino)phenyl)-3-ph
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    Mol. Formula:
    C22H19N5O2

    M.W.:
    385.43

    Type:
    Unknown

    AlogP:
    5.03

    Polar Surface Area:
    88.17

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  9. ALA4876562

    Name:
    1-(4-((6-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C23H21N5O2

    M.W.:
    399.45

    Type:
    Unknown

    AlogP:
    5.13

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  10. ALA4876396

    Name:
    1-(3,4-Dimethoxybenzyl)-3-(4-((7-(dimethylamino)qu
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    Mol. Formula:
    C26H27N5O4

    M.W.:
    473.53

    Type:
    Unknown

    AlogP:
    4.83

    Polar Surface Area:
    97.84

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  11. ALA4874053

    Name:
    1-(4-(7-(dimethylamino)quinazolin-4-yloxy)phenyl)-
    Show More

    Mol. Formula:
    C24H20F3N5O2

    M.W.:
    467.45

    Type:
    Unknown

    AlogP:
    6.15

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  12. ALA4873828

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
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    Mol. Formula:
    C24H23N5O2

    M.W.:
    413.48

    Type:
    Unknown

    AlogP:
    4.81

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  13. ALA4872597

    Name:
    1-(4-((7-Methoxyquinazolin-4-yl)oxy)phenyl)-3-phen
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    Mol. Formula:
    C22H18N4O3

    M.W.:
    386.41

    Type:
    Unknown

    AlogP:
    5.07

    Polar Surface Area:
    85.37

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.50

    DETAILS
  14. ALA4871989

    Name:
    1-Phenyl-3-(4-((7-(pyrrolidin-1-yl)quinazolin-4-yl
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    Mol. Formula:
    C25H23N5O2

    M.W.:
    425.49

    Type:
    Unknown

    AlogP:
    5.67

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  15. ALA4871756

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)amino)phen
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    Mol. Formula:
    C23H22N6O

    M.W.:
    398.47

    Type:
    Unknown

    AlogP:
    5.08

    Polar Surface Area:
    82.18

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  16. ALA4871510

    Name:
    1-(4-((7-Fluoroquinazolin-4-yl)oxy)phenyl)-3-pheny
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    Mol. Formula:
    C21H15FN4O2

    M.W.:
    374.38

    Type:
    Unknown

    AlogP:
    5.21

    Polar Surface Area:
    76.14

    HBA:
    4

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  17. ALA4870448

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
    Show More

    Mol. Formula:
    C25H25N5O3

    M.W.:
    443.51

    Type:
    Unknown

    AlogP:
    4.82

    Polar Surface Area:
    88.61

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  18. ALA4870360

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
    Show More

    Mol. Formula:
    C24H24N6O3

    M.W.:
    444.50

    Type:
    Unknown

    AlogP:
    4.21

    Polar Surface Area:
    101.50

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  19. ALA4867079

    Name:
    1-(3-Chlorophenyl)-3-(5-(2-((7-fluoroquinazolin-4-
    Show More

    Mol. Formula:
    C20H16ClFN6OS

    M.W.:
    442.91

    Type:
    Unknown

    AlogP:
    5.18

    Polar Surface Area:
    91.83

    HBA:
    6

    HBD:
    3

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  20. ALA4866196

    Name:
    1-(4-((7-(Dimethylamino)quinazolin-4-yl)oxy)phenyl
    Show More

    Mol. Formula:
    C24H18F5N5O2

    M.W.:
    503.43

    Type:
    Unknown

    AlogP:
    5.51

    Polar Surface Area:
    79.38

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.21

    DETAILS
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