Compounds

ALA5287697

Name:
1-Isopropyl-3-{3-[1-(tetrahydro-pyran-4-ylmethyl)-
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Mol. Formula:
C25H33N5O6

M.W.:
499.57

Type:
---

AlogP:
4.27

Polar Surface Area:
69.21

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.63

DETAILS

ALA5287000

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid[8-(2-flu
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Mol. Formula:
C20H27FN4O

M.W.:
358.46

Type:
---

AlogP:
3.31

Polar Surface Area:
50.16

HBA:
4

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.89

DETAILS

ALA5286989

Name:
3-[5-(1-Cyclobutylmethyl-piperidin-4-yl)-[1,3,4]ox
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Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
4.65

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5286814

Name:
3-[5-(1-Cyclopentyl-piperidin-4-yl)-[1,3,4]oxadiaz
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Mol. Formula:
C22H29N5O

M.W.:
379.51

Type:
---

AlogP:
4.79

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.65

DETAILS

ALA5286642

Name:
1-Isopropyl-3-[5-(1-phenethyl-piperidin-4-yl)-[1,3
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Mol. Formula:
C27H31N5O5

M.W.:
505.58

Type:
---

AlogP:
5.09

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.44

DETAILS

ALA5286398

Name:
3-[5-(1-Cyclopropylmethyl-piperidin-4-yl)-[1,3,4]o
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Mol. Formula:
C21H27N5O

M.W.:
365.48

Type:
---

AlogP:
4.26

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.68

DETAILS

ALA5286277

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid [1-(tetr
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Mol. Formula:
C26H38N4O8

M.W.:
534.61

Type:
---

AlogP:
3.24

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
5

Passes Ro3:
N

QED Weighted:
0.86

DETAILS

ALA5286257

Name:
1-Isopropyl-1H-indazole-3-carboxylic Acid[4-Hydrox
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Mol. Formula:
C22H32N4O7

M.W.:
464.52

Type:
---

AlogP:
2.17

Polar Surface Area:
79.62

HBA:
6

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.57

DETAILS

ALA5285645

Name:
2-(6-(4-(((1-(phenylsulfonyl-1H-indol-4-yl)methypp
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Mol. Formula:
C34H39N5O3S2

M.W.:
629.85

Type:
---

AlogP:
5.43

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.21

DETAILS

ALA5285364

Name:
1-isopropyl-3-[5-[1-(3-methoxypropyl)-piperidin-4-
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Mol. Formula:
C21H29N5O2

M.W.:
383.50

Type:
---

AlogP:
3.88

Polar Surface Area:
69.21

HBA:
7

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.58

DETAILS

ALA5284727

Name:
2-(4-(4-((1-(phenylsulfonyl)-1H-indol-4-yl)methyl)
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Mol. Formula:
C33H37N5O3S2

M.W.:
615.83

Type:
---

AlogP:
5.04

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
9

Passes Ro3:
N

QED Weighted:
0.25

DETAILS

ALA5284140

Name:
1-Isopropyl-1H-indazole-3-carboxylic acid[1-(3-hyd
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Mol. Formula:
C21H33ClN4O2

M.W.:
408.97

Type:
---

AlogP:
2.83

Polar Surface Area:
70.39

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.82

DETAILS

ALA5283896

Name:
2-(6-(4-((1-(phenylsulfonyl)-1H-indol-4-yl)methyl)
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Mol. Formula:
C35H41N5O3S2

M.W.:
643.88

Type:
---

AlogP:
5.82

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
11

Passes Ro3:
N

QED Weighted:
0.19

DETAILS

ALA5283820

Name:
1-Isopropyl-3-[5-(1-isopropyl-piperidin-4-yl)-[1,2
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Mol. Formula:
C20H27N5O

M.W.:
353.47

Type:
---

AlogP:
4.26

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5283579

Name:
3-[5-(1-Cyclopropyl-piperidin-4-yl)-[1,3,4]oxadiaz
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Mol. Formula:
C22H27N5O5

M.W.:
441.49

Type:
---

AlogP:
4.01

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.71

DETAILS

ALA5283568

Name:
3-{4-[(1-Isopropyl-1H-indazole-3-carbonyl)-amino]-
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Mol. Formula:
C25H36N4O9

M.W.:
536.58

Type:
---

AlogP:
2.92

Polar Surface Area:
87.46

HBA:
5

HBD:
2

#RO5 Violations:
---

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.80

DETAILS

ALA5283556

Name:
1-Isopropyl-7H-indazole-3-carboxylic Acid[8-(2-Flu
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Mol. Formula:
C22H32N4O2

M.W.:
384.52

Type:
---

AlogP:
3.38

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.74

DETAILS

ALA5283534

Name:
3-[5-(3-Cyclobutyl-3-aza-bicyclo[3.1.0]hex-6-yl)-[
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Mol. Formula:
C23H27N5O5

M.W.:
453.50

Type:
---

AlogP:
3.86

Polar Surface Area:
59.98

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.70

DETAILS

ALA5283058

Name:
1-Isopropyl-1H-indazole-3-carboxylic Acid[1-(3-Met
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Mol. Formula:
C22H32N4O6

M.W.:
448.52

Type:
---

AlogP:
2.85

Polar Surface Area:
59.39

HBA:
5

HBD:
1

#RO5 Violations:
---

#Rotatable Bonds:
7

Passes Ro3:
N

QED Weighted:
0.77

DETAILS

ALA5282158

Name:
2-(7-(4-((1-(phenylsulfonyl)-1H-indol-4-yl)methyl)
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Mol. Formula:
C36H43N5O3S2

M.W.:
657.91

Type:
---

AlogP:
6.21

Polar Surface Area:
78.22

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.17

DETAILS