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  1. ALA4745102

    Name:
    (R)-2-(5-(4-((1-(2-Fluoro-5-(pyrrolidin-1-yl)pheny
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    Mol. Formula:
    C28H30FN5O

    M.W.:
    471.58

    Type:
    Unknown

    AlogP:
    5.83

    Polar Surface Area:
    74.17

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  2. ALA4744981

    Name:
    rac-2-(5-(3-Chloro-8-fluoro-4-((1-(2-fluorophenyl)
    Show More

    Mol. Formula:
    C24H21ClF2N4O

    M.W.:
    454.91

    Type:
    Unknown

    AlogP:
    6.02

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  3. ALA4744215

    Name:
    5-(4-((2,5-Dimethylphenyl)amino)quinolin-6-yl)pico
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    Mol. Formula:
    C23H18N4

    M.W.:
    350.43

    Type:
    Unknown

    AlogP:
    5.53

    Polar Surface Area:
    61.60

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  4. ALA4743885

    Name:
    (+/-)-2-(5-(3-Chloro-4-((1-(pyridin-2-yl)ethyl)ami
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    Mol. Formula:
    C23H22ClN5O

    M.W.:
    419.92

    Type:
    Unknown

    AlogP:
    5.14

    Polar Surface Area:
    83.82

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  5. ALA4743794

    Name:
    rac-2-(5-(3,5-Dichloro-4-((1-(2-fluorophenyl)ethyl
    Show More

    Mol. Formula:
    C24H21Cl2FN4O

    M.W.:
    471.36

    Type:
    Unknown

    AlogP:
    6.54

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  6. Type:
    Unknown

    AlogP:
    4.58

    Polar Surface Area:
    68.76

    HBA:
    6

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  7. ALA4742834

    Name:
    (+/-)-2-(5-(3-Chloro-4-((1-(4-fluorophenyl)ethyl)a
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    Mol. Formula:
    C24H22ClFN4O

    M.W.:
    436.92

    Type:
    Unknown

    AlogP:
    5.88

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  8. ALA4742065

    Name:
    (+/-)-2-(5-(7-Chloro-8-((1-(2-fluorophenyl)ethyl)a
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    Mol. Formula:
    C23H21ClFN5O

    M.W.:
    437.91

    Type:
    Unknown

    AlogP:
    5.28

    Polar Surface Area:
    83.82

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  9. ALA4741635

    Name:
    (+/-)-2-(5-(6-Chloro-5-((1-(2-fluorophenyl)ethyl)a
    Show More

    Mol. Formula:
    C23H21ClFN5O

    M.W.:
    437.91

    Type:
    Unknown

    AlogP:
    5.28

    Polar Surface Area:
    83.82

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  10. ALA4776281

    Name:
    5-(3-Chloro-4-((2,5-dimethylphenyl)amino)quinolin-
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    Mol. Formula:
    C23H17ClN4

    M.W.:
    384.87

    Type:
    Unknown

    AlogP:
    6.18

    Polar Surface Area:
    61.60

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  11. ALA4776179

    Name:
    rac-2-(5-(3,7-Dichloro-4-((1-(2-fluorophenyl)ethyl
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    Mol. Formula:
    C24H21Cl2FN4O

    M.W.:
    471.36

    Type:
    Unknown

    AlogP:
    6.54

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  12. ALA4764442

    Name:
    (R)-2-(4-(3-Chloro-4-((1-(2-fluorophenyl)ethyl)ami
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    Mol. Formula:
    C26H24ClFN2O

    M.W.:
    434.94

    Type:
    Unknown

    AlogP:
    7.09

    Polar Surface Area:
    45.15

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  13. ALA4764418

    Name:
    2-(5-(3-Chloro-4-((2,5-dimethylphenyl)amino)-2-met
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    Mol. Formula:
    C25H25ClN4O

    M.W.:
    432.96

    Type:
    Unknown

    AlogP:
    6.24

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  14. ALA4763313

    Name:
    (+/-)-2-(5-(3-Chloro-4-((1-(3-fluorophenyl)ethyl)a
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    Mol. Formula:
    C24H22ClFN4O

    M.W.:
    436.92

    Type:
    Unknown

    AlogP:
    5.88

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  15. ALA4763268

    Name:
    (S)-2-(5-(3-Chloro-4-((1-phenylethyl)amino)quinoli
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    Mol. Formula:
    C24H23ClN4O

    M.W.:
    418.93

    Type:
    Unknown

    AlogP:
    5.75

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  16. ALA4762023

    Name:
    (+/-)-2-(5-(3-Chloro-4-((1-(2-fluorophenyl)ethyl)a
    Show More

    Mol. Formula:
    C24H22ClFN4O

    M.W.:
    436.92

    Type:
    Unknown

    AlogP:
    5.88

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  17. ALA4759848

    Name:
    (R)-3-(1-((3-Chloro-6-(2-(2-hydroxypropan-2-yl)pyr
    Show More

    Mol. Formula:
    C25H21ClFN5O

    M.W.:
    461.93

    Type:
    Unknown

    AlogP:
    5.76

    Polar Surface Area:
    94.72

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  18. ALA4758143

    Name:
    rac-2-(5-(3,8-Dichloro-4-((1-(2-fluorophenyl)ethyl
    Show More

    Mol. Formula:
    C24H21Cl2FN4O

    M.W.:
    471.36

    Type:
    Unknown

    AlogP:
    6.54

    Polar Surface Area:
    70.93

    HBA:
    5

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  19. ALA4779860

    Name:
    1-(2-(difluoromethoxy)benzyl)-2,2-dimethylindolin-
    Show More

    Mol. Formula:
    C18H17F2NO2

    M.W.:
    317.34

    Type:
    Unknown

    AlogP:
    4.27

    Polar Surface Area:
    29.54

    HBA:
    3

    HBD:
    ---

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS
  20. ALA4779359

    Name:
    8-(4-(2-(5-((4-methylpiperazin-1-yl)methyl)-2-(1H-
    Show More

    Mol. Formula:
    C36H35N5O

    M.W.:
    553.71

    Type:
    Unknown

    AlogP:
    6.81

    Polar Surface Area:
    57.28

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS
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