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  1. ALA4877547

    Name:
    N-cyclopropyl-4-(7-(2-((trans)-3-hydroxy-3-methylc
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    Mol. Formula:
    C29H31N5O3

    M.W.:
    497.60

    Type:
    Unknown

    AlogP:
    4.88

    Polar Surface Area:
    101.64

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  2. ALA4875028

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
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    Mol. Formula:
    C33H45N7O3

    M.W.:
    587.77

    Type:
    Unknown

    AlogP:
    4.78

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  3. ALA4874692

    Name:
    N-((1S,4S)-4-(5-ethyl-2-((2-methoxy-4-(4-methylpip
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    Mol. Formula:
    C30H41N7O3

    M.W.:
    547.70

    Type:
    Unknown

    AlogP:
    3.87

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  4. ALA4873395

    Name:
    (3R,5R,7R)-N-((1S,4S)-4-(24(2-methoxy-4-(4-methylp
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    Mol. Formula:
    C37H49N7O3

    M.W.:
    639.84

    Type:
    Unknown

    AlogP:
    5.42

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.35

    DETAILS
  5. ALA4870731

    Name:
    8-((1S,4S)-4-((cyclopropylmethyl)amino)cyclohexyl)
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    Mol. Formula:
    C30H41N7O2

    M.W.:
    531.71

    Type:
    Unknown

    AlogP:
    4.09

    Polar Surface Area:
    87.55

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  6. ALA4870223

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
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    Mol. Formula:
    C32H43N7O3

    M.W.:
    573.74

    Type:
    Unknown

    AlogP:
    4.39

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  7. ALA4869527

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
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    Mol. Formula:
    C29H39N7O3

    M.W.:
    533.68

    Type:
    Unknown

    AlogP:
    3.61

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  8. ALA4869142

    Name:
    N-((1S,4S)-4-(5-methyl-2-((2-methyl-4-(4-methylpip
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    Mol. Formula:
    C29H39N7O2

    M.W.:
    517.68

    Type:
    Unknown

    AlogP:
    3.91

    Polar Surface Area:
    95.39

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  9. ALA4867504

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
    Show More

    Mol. Formula:
    C30H41N7O3

    M.W.:
    547.70

    Type:
    Unknown

    AlogP:
    3.86

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  10. ALA4866294

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
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    Mol. Formula:
    C28H37N7O3

    M.W.:
    519.65

    Type:
    Unknown

    AlogP:
    3.31

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.49

    DETAILS
  11. ALA4863607

    Name:
    N-((1S,4S)-4-(5-methyl-2-((3-methyl-4-(4-methylpip
    Show More

    Mol. Formula:
    C29H39N7O2

    M.W.:
    517.68

    Type:
    Unknown

    AlogP:
    3.91

    Polar Surface Area:
    95.39

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  12. ALA4859127

    Name:
    2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)ami
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    Mol. Formula:
    C28H37N7O3

    M.W.:
    519.65

    Type:
    Unknown

    AlogP:
    3.18

    Polar Surface Area:
    95.83

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
  13. ALA4858486

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
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    Mol. Formula:
    C33H45N7O3

    M.W.:
    587.77

    Type:
    Unknown

    AlogP:
    4.78

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  14. ALA4857210

    Name:
    cis-N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperaz
    Show More

    Mol. Formula:
    C29H39N7O3

    M.W.:
    533.68

    Type:
    Unknown

    AlogP:
    3.61

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.47

    DETAILS
  15. ALA4856340

    Name:
    2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)ami
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    Mol. Formula:
    C26H33N7O3

    M.W.:
    491.60

    Type:
    Unknown

    AlogP:
    2.40

    Polar Surface Area:
    95.83

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    ---

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  16. ALA4861308

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
    Show More

    Mol. Formula:
    C28H37N7O3

    M.W.:
    519.65

    Type:
    Unknown

    AlogP:
    3.22

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.51

    DETAILS
  17. ALA4860644

    Name:
    (R)-2((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)
    Show More

    Mol. Formula:
    C27H35N7O3

    M.W.:
    505.62

    Type:
    Unknown

    AlogP:
    2.79

    Polar Surface Area:
    95.83

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  18. ALA4860430

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
    Show More

    Mol. Formula:
    C30H39N7O3

    M.W.:
    545.69

    Type:
    Unknown

    AlogP:
    3.61

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.46

    DETAILS
  19. ALA4859914

    Name:
    N-((1S,4S)-4-(2-((2-methoxy-4-(4-methylpiperazin-1
    Show More

    Mol. Formula:
    C37H41N7O3

    M.W.:
    631.78

    Type:
    Unknown

    AlogP:
    5.67

    Polar Surface Area:
    104.62

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  20. ALA4849289

    Name:
    (S)-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl
    Show More

    Mol. Formula:
    C28H37N7O3

    M.W.:
    519.65

    Type:
    Unknown

    AlogP:
    3.18

    Polar Surface Area:
    95.83

    HBA:
    9

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.53

    DETAILS
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