Type:
Small molecule

AlogP:
6.54

Polar Surface Area:
60.42

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.30

Type:
Small molecule

AlogP:
6.54

Polar Surface Area:
60.42

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.30

Type:
Small molecule

AlogP:
6.58

Polar Surface Area:
81.08

HBA:
6

HBD:
2

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.21

Type:
Small molecule

AlogP:
5.02

Polar Surface Area:
81.08

HBA:
6

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.37

Type:
Small molecule

AlogP:
5.51

Polar Surface Area:
74.60

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.42

Type:
Small molecule

AlogP:
4.94

Polar Surface Area:
129.98

HBA:
10

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.24

Type:
Small molecule

AlogP:
6.20

Polar Surface Area:
74.60

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.35

Type:
Small molecule

AlogP:
6.20

Polar Surface Area:
74.60

HBA:
4

HBD:
2

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.35

Type:
Small molecule

AlogP:
5.84

Polar Surface Area:
86.74

HBA:
6

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
6

Passes Ro3:
N

QED Weighted:
0.26

Type:
Small molecule

AlogP:
4.55

Polar Surface Area:
105.20

HBA:
8

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.27

Type:
Small molecule

AlogP:
4.35

Polar Surface Area:
173.02

HBA:
10

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.14

Type:
Small molecule

AlogP:
4.35

Polar Surface Area:
173.02

HBA:
10

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.14

Type:
Small molecule

AlogP:
7.19

Polar Surface Area:
59.08

HBA:
6

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.16

Type:
Small molecule

AlogP:
5.55

Polar Surface Area:
107.98

HBA:
10

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
14

Passes Ro3:
N

QED Weighted:
0.18

Type:
Small molecule

AlogP:
4.68

Polar Surface Area:
78.88

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
8

Passes Ro3:
N

QED Weighted:
0.42

Type:
Small molecule

AlogP:
5.53

Polar Surface Area:
89.52

HBA:
8

HBD:
---

#RO5 Violations:
2

#Rotatable Bonds:
12

Passes Ro3:
N

QED Weighted:
0.23

Type:
Small molecule

AlogP:
5.51

Polar Surface Area:
71.06

HBA:
6

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
10

Passes Ro3:
N

QED Weighted:
0.29

Type:
Small molecule

AlogP:
4.42

Polar Surface Area:
86.70

HBA:
6

HBD:
---

#RO5 Violations:
---

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.44

Type:
Small molecule

AlogP:
5.25

Polar Surface Area:
78.88

HBA:
6

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
4

Passes Ro3:
N

QED Weighted:
0.37

Type:
Small molecule

AlogP:
5.85

Polar Surface Area:
60.42

HBA:
4

HBD:
---

#RO5 Violations:
1

#Rotatable Bonds:
2

Passes Ro3:
N

QED Weighted:
0.35