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  1. ALA4589373

    Name:
    4-(2-(3-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trif
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    Mol. Formula:
    C29H30F3N7O3S

    M.W.:
    613.67

    Type:
    Unknown

    AlogP:
    5.64

    Polar Surface Area:
    111.72

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  2. ALA4861080

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C29H32ClF2N7O2

    M.W.:
    584.07

    Type:
    Unknown

    AlogP:
    5.45

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  3. ALA4858755

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C29H33ClF2N8O2

    M.W.:
    599.09

    Type:
    Unknown

    AlogP:
    4.21

    Polar Surface Area:
    96.94

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  4. ALA4856927

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C30H32ClF2N7O3S

    M.W.:
    644.15

    Type:
    Unknown

    AlogP:
    4.78

    Polar Surface Area:
    102.93

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  5. ALA4876323

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C31H34ClF2N7O3

    M.W.:
    626.11

    Type:
    Unknown

    AlogP:
    5.22

    Polar Surface Area:
    102.93

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  6. ALA4875912

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C32H36ClF2N7O2

    M.W.:
    624.14

    Type:
    Unknown

    AlogP:
    6.38

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.32

    DETAILS
  7. ALA4849644

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C31H34ClF2N7O3

    M.W.:
    626.11

    Type:
    Unknown

    AlogP:
    5.22

    Polar Surface Area:
    102.93

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  8. ALA4848423

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C28H30ClF2N7O2S

    M.W.:
    602.11

    Type:
    Unknown

    AlogP:
    5.01

    Polar Surface Area:
    93.70

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  9. ALA4846567

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C29H32ClF2N7O2

    M.W.:
    584.07

    Type:
    Unknown

    AlogP:
    5.45

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  10. ALA4846244

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C31H34ClF2N7O2S

    M.W.:
    642.18

    Type:
    Unknown

    AlogP:
    5.94

    Polar Surface Area:
    93.70

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  11. ALA4845827

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C28H30ClF2N7O3

    M.W.:
    586.04

    Type:
    Unknown

    AlogP:
    4.30

    Polar Surface Area:
    102.93

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  12. ALA4865553

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C31H34ClF2N7O2

    M.W.:
    610.11

    Type:
    Unknown

    AlogP:
    5.99

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  13. ALA4854719

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
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    Mol. Formula:
    C32H37ClF2N8O2

    M.W.:
    639.15

    Type:
    Unknown

    AlogP:
    5.14

    Polar Surface Area:
    96.94

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.37

    DETAILS
  14. ALA4854103

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C31H35ClF2N8O2S

    M.W.:
    657.19

    Type:
    Unknown

    AlogP:
    4.70

    Polar Surface Area:
    96.94

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.38

    DETAILS
  15. ALA4853913

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C29H33ClF2N8O2

    M.W.:
    599.09

    Type:
    Unknown

    AlogP:
    4.21

    Polar Surface Area:
    96.94

    HBA:
    8

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.42

    DETAILS
  16. ALA4853874

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C31H36ClF2N7O2

    M.W.:
    612.12

    Type:
    Unknown

    AlogP:
    6.23

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.30

    DETAILS
  17. ALA4852786

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C31H35ClF2N8O3

    M.W.:
    641.12

    Type:
    Unknown

    AlogP:
    3.98

    Polar Surface Area:
    106.17

    HBA:
    9

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  18. ALA4871876

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C28H30ClF2N7O2

    M.W.:
    570.04

    Type:
    Unknown

    AlogP:
    5.06

    Polar Surface Area:
    93.70

    HBA:
    7

    HBD:
    2

    #RO5 Violations:
    2

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.41

    DETAILS
  19. ALA4868222

    Name:
    (S)-1-(5-chloro-2-((3,5-difluorophenyl)amino)pyrim
    Show More

    Mol. Formula:
    C29H32ClF2N7O3

    M.W.:
    600.07

    Type:
    Unknown

    AlogP:
    4.47

    Polar Surface Area:
    122.72

    HBA:
    8

    HBD:
    4

    #RO5 Violations:
    1

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.28

    DETAILS
  20. ALA4649835

    Name:
    N-(2-(2-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoi
    Show More

    Mol. Formula:
    C44H46FN11O6

    M.W.:
    843.92

    Type:
    Unknown

    AlogP:
    3.04

    Polar Surface Area:
    186.71

    HBA:
    14

    HBD:
    3

    #RO5 Violations:
    2

    #Rotatable Bonds:
    14

    Passes Ro3:
    N

    QED Weighted:
    0.11

    DETAILS
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