DB0614 , CAS No.2769753-47-9

Item Number

D646495

Grouped product items
SKU	Size	Availability	Price
D646495-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$875.90
D646495-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$216.90
D646495-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$541.90

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Basic Description

Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1 , AURKA, BMP2K, CAMKK1, CDK16 , CML, CDK6 , EIF2AK2, FER, GAK, LCK, LIMK2 , MAP3KH, MAPK8, MAPK9, NEK9, PLK4 , PTK2B, SIK2 , STK17A, STK17B, ULK1 , ULK3, and WEE1 . DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity IC50& Target:CDK6 CDK16/Cyclin Y ULK1 Aurora Kinase SIK2 LIMK2

Canonical SMILES

O=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(OCCCCCN4CCN(CC4)C5=CC=C(NC6=NC7=C(SC=C7C8=CC(NS(=O)(C)=O)=CC=C8)C=N6)C=C5)=CC=C2

Molecular Weight

822.95

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Basic Description