DBCO-PEG4-Desthiobiotin - 95%, high purity , CAS No.2032788-37-5

Item Number

D595738

Grouped product items
SKU	Size	Availability	Price
D595738-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$538.90
D595738-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$988.90
D595738-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,886.90

Biotin PEG-DBCO

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Basic Description

Specifications & Purity	95%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	DBCO-PEG4-Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd锞? 1011锞妚s. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. DBCO is commonly used for copper-free Click Chemistry reactions.

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Basic Description