DBCO-PEG4-Desthiobiotin - 95%, high purity , CAS No.2032788-37-5

  • ≥95%
Item Number
D595738
Grouped product items
SKUSizeAvailabilityPrice Qty
D595738-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$538.90
D595738-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$988.90
D595738-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,886.90

Biotin PEG-DBCO

View related series
Biotin PEG

Basic Description

Specifications & Purity95%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

DBCO-PEG4-Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd锞? 1011锞妚s. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. DBCO is commonly used for copper-free Click Chemistry reactions.

Names and Identifiers

Molecular Weight 719.9

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