DBCO-PEG4-GGFG-Exatecan - 98%, high purity , CAS No.2694856-51-2

  • ≥98%
Item Number
D646155
Grouped product items
SKUSizeAvailabilityPrice Qty
D646155-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$712.90
D646155-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,215.90

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsDBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is a agent-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is a agent-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Traditional Cytotoxic Agents

Names and Identifiers

Canonical SMILES O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[C@@H]5NC(COCNC(CNC([C@H](CC6=CC=CC=C6)NC(CNC(CNC(CCOCCOCCOCCOCCNC(CCC(N7C8=CC=CC=C8C#CC9=CC=CC=C9C7)=O)=O)=O)=O)=O)=O)=O)=O)=C4C5=C3C%10)N%10C2=O)[C@]1(CC)O
Molecular Weight 1375.45

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 50 mg/mL (36.35 mM; ultrasonic and warming and heat to 60°C)

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Solution Calculators