DBCO-PEG4-GGFG-Exatecan (DBCO-PEG4-GGFG-DX8951) is a agent-linker conjugate for ADC with potent antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke. MCE has not independently confirmed the accuracy of these methods. They are for reference only.