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SKU | Size | Availability | Price | Qty |
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D647675-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $680.90 | |
D647675-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,350.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 1 |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | DBCO-PEG4-VC-PAB-MMAE consists an ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates ( ADC s). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization Form:Solid IC50& Target:Duocarmycins |
Canonical SMILES | CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N4CC5=C(C=CC=C5)C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)C=C |
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Molecular Weight | 1658.03 |
Solubility | DMSO : 150 mg/mL (90.47 mM; Need ultrasonic) |
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