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DBCO-PEG4-VC-PAB-MMAE - 99%, high purity , CAS No.2129164-91-4

  • ≥99%
Item Number
D647675
Grouped product items
SKUSizeAvailabilityPrice Qty
D647675-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$680.90
D647675-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,350.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsDBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 1
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

DBCO-PEG4-VC-PAB-MMAE consists an ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE ( HY-15162 ). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates ( ADC s). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization

Form:Solid

IC50& Target:Duocarmycins

Names and Identifiers

Canonical SMILES CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCC(N4CC5=C(C=CC=C5)C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)C=C
Molecular Weight 1658.03

Certificates

C of A & Other Certificates(BSE/TSE, COO)

Chemical and Physical Properties

SolubilityDMSO : 150 mg/mL (90.47 mM; Need ultrasonic)

Related Documents

Solution Calculators