JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

dBET23 - 99%, high purity , CAS No.1957234-83-1

Item Number

D646520

Grouped product items
SKU	Size	Availability	Price
D646520-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,800.90
D646520-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$390.90
D646520-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,150.90

View related series

Basic Description

Specifications & Purity	99%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Dry ice
Product Description	dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC 50/5h of ~ 50 nM for BRD4 BD1 protein. In Vitro dBET23 occupies the canonical binding sites on CRBN and BRD4 BD1 for thalidomide and JQ1, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Canonical SMILES	O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCCCCNC(COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1
Molecular Weight	885.38

Enter Lot Number to search for COA:

Solubility	DMSO : 110 mg/mL (124.24 mM; ultrasonic and warming and heat to 60°C)

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.