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dBRD9 , CAS No.2170679-45-3, bromodomain containing 9;cereblon

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dBRD9 , CAS No.2170679-45-3, bromodomain containing 9;cereblon

Moligand™

CAS#: 2170679-45-3
PubChem CID: 135397681

Item Number

D609754

Grouped product items
SKU	Size	Availability	Price	Qty
D609754-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D609754-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

bromodomain containing 9 cereblon

Basic Description

Synonyms	Naphthiridinone degrader 6
Grade	Moligand™
Mechanism of action	bromodomain containing 9;cereblon

Associated Targets

CRBN Tclin Protein cereblon 0 Activities

Discover Target: CRBN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRD9 Tchem Bromodomain-containing protein 9 0 Activities

Discover Target: BRD9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-[[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyridin-4-yl)phenyl]methyl-methylamino]-N-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide
INCHI	InChI=1S/C40H45N7O10/c1-45(21-29-32(54-3)18-24(19-33(29)55-4)28-22-46(2)38(51)27-20-41-11-10-25(27)28)23-35(49)43-13-15-57-17-16-56-14-12-42-30-7-5-6-26-36(30)40(53)47(39(26)52)31-8-9-34(48)44-37(31)50/h5-7,10-11,18-20,22,31,42H,8-9,12-17,21,23H2,1-4H3,(H,43,49)(H,44,48,50)
InChi Key	AIOCFZJGGGEWDK-UHFFFAOYSA-N
Canonical SMILES	CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)CC(=O)NCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)OC
PubChem CID	135397681

Database links

PubChem CID	135397681
CAS Registry No.	2170679-45-3

Certificates

Certificate of Analysis(COA)

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References

1. Remillard D, Buckley DL, Paulk J, Brien GL, Sonnett M, Seo HS, Dastjerdi S, Wühr M, Dhe-Paganon S, Armstrong SA et al.. (2017) Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.. Angew Chem Int Ed Engl, 56 (21): (5738-5743). [PMID:28418626]

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