DC_517 - 99%, high purity , CAS No.500017-70-9

Item Number

D646685

Grouped product items
SKU	Size	Availability	Price
D646685-2mg	2mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$194.90
D646685-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$420.90
D646685-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$720.90
D646685-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,160.90

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Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	DC_517 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	DC_517 is a DNA methyltransferase 1 ( DNMT1 ) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. In Vitro DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC 50 and a K d of 1.7 μM and 0.91 μM, respectively. DC_517 (1.25, 2.5, 5, and 10 μM) potently inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC_517 (0, 0.75, 1.5, and 3 μM) also dose-dependently induces apoptotic cell death in HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:DNMT1 0.91 μM (Kd) DNMT1 1.7 μM (IC 50 )

Canonical SMILES

OC(CNC(C)C)COC(CN1C(C=CC=C2)=C2C3=C1C=CC=C3)CN(C4=CC=CC=C45)C6=C5C=CC=C6

Molecular Weight

505.65

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Basic Description