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DCG IV - ≥98%(HPLC), high purity , CAS No.147782-19-2, Antagonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor

Moligand™
≥98%(HPLC)

CAS#: 147782-19-2
Formula: C₇H₉NO₆
Molecular Weight: 203.15
PubChem CID: 5310979

Item Number

D288585

Grouped product items
SKU	Size	Availability	Price
D288585-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$224.90
D288585-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$483.90
D288585-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,971.90

Highly potent group II mGlu agonist; also NMDA agonist

View related series

mGlu1 receptor Antagonist mGlu2 receptor Agonist mGlu3 receptor Agonist mGlu5 receptor Antagonist mGlu6 receptor Antagonist mGlu7 receptor Antagonist mGlu8 receptor Antagonist

Basic Description

Synonyms	Dcg-IV\|147782-19-2\|(1r,2r)-3-[(S)-Amino(Carboxy)methyl]cyclopropane-1,2-Dicarboxylic Acid\|CHEMBL284193\|1,2-Cyclopropanedicarboxylic acid, 3-[(S)-aminocarboxymethyl]-, (1R,2R)-\|DCGIV\|SCHEMBL658075\|GTPL1377\|MATPZHBYOVDBLI-JJYYJPOSSA-N\|BDBM50034503\|AKOS03023
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Presynaptic depressant; highly potent agonist for group II mGlu receptors.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST, ANTAGONIST
Mechanism of action	Antagonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor

Associated Targets

GRM1 Tchem Metabotropic glutamate receptor 1 1 Activities

Discover Target: GRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM2 Tchem Metabotropic glutamate receptor 2 2 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM4 Tchem Metabotropic glutamate receptor 4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM5 Tchem Metabotropic glutamate receptor 5 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM7 Tchem Metabotropic glutamate receptor 7 1 Activities

Discover Target: GRM7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM8 Tchem Metabotropic glutamate receptor 8 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM3 Tchem Metabotropic glutamate receptor 3 2 Activities

Discover Target: GRM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRM6 Tchem Metabotropic glutamate receptor 6 1 Activities

Discover Target: GRM6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1R,2R)-3-[(S)-amino(carboxy)methyl]cyclopropane-1,2-dicarboxylic acid
INCHI	InChI=1S/C7H9NO6/c8-4(7(13)14)1-2(5(9)10)3(1)6(11)12/h1-4H,8H2,(H,9,10)(H,11,12)(H,13,14)/t2-,3-,4+/m1/s1
InChi Key	MATPZHBYOVDBLI-JJYYJPOSSA-N
Canonical SMILES	C1(C(C1C(=O)O)C(=O)O)C(C(=O)O)N
Isomeric SMILES	[C@@H]1([C@@H](C1[C@@H](C(=O)O)N)C(=O)O)C(=O)O
PubChem CID	5310979
Molecular Weight	203.15

PubChem CID

BindingDB Ligand

CAS Registry No.

ChEMBL Ligand

RCSB PDB Ligand

GPCRdb Ligand

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation H302:Harmful if swallowed
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help.

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