Dehydrocostus lactone - 10mM in DMSO, high purity , CAS No.477-43-0

Item Number

D424153

Grouped product items
SKU	Size	Availability	Price	Qty
D424153-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90

Cell proliferation inhibitor, induces cell cycle arrest and apoptosis

Basic Description

Synonyms	Dehydrocostus lactone\|477-43-0\|dehydrocostuslactone\|Epiligulyl oxide\|(-)-dehydrocostus lactone\|71TRF5K040\|(-)-dehydrocostuslactone\|COSTUS LACTONE, DEHYDRO-\|CHEBI:244418\|(3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one\|DEHYDROCOST
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Cell proliferation inhibitor, induces cell cycle arrest and apoptosis. Inhibits NO synthase and TNF-α in LPS-activated macrophages. Cytotoxic T lymphocyte inhibitor in vitro (IC 50 = 10 μM). Guaianolide. Immunomodulator and antitumor agent.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one
INCHI	InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1
InChi Key	NETSQGRTUNRXEO-XUXIUFHCSA-N
Canonical SMILES	C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C
Isomeric SMILES	C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C
PubChem CID	73174
Molecular Weight	230.31

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse.

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Basic Description