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Desmethyl Thiosildenafil , CAS No.479073-86-4
Basic Description
Synonyms | AKOS030242134 | DTXSID30436111 | Piperazine, 1-((3-(4,7-dihydro-1-methyl-3-propyl-7-thioxo-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)- | Desmethylthiosildenafil | 7H-Pyrazolo(4,3-d)pyrimidine-7-thione, 5-(2-ethoxy-5-(1-piperazinylsulfonyl) |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Desmethyl Thiosildenafil is a Sildenafil thiono analog, and a novel pyrazolopyrimidinethione and a PDE5 inhibitor. |
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Names and Identifiers
IUPAC Name | 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione |
INCHI | InChI=1S/C21H28N6O3S2/c1-4-6-16-18-19(26(3)25-16)21(31)24-20(23-18)15-13-14(7-8-17(15)30-5-2)32(28,29)27-11-9-22-10-12-27/h7-8,13,22H,4-6,9-12H2,1-3H3,(H,23,24,31) |
InChi Key | VMDTWBKYCKLNLA-UHFFFAOYSA-N |
Canonical SMILES | CCCC1=NN(C2=C1NC(=NC2=S)C3=C(C=CC(=C3)S(=O)(=O)N4CCNCC4)OCC)C |
Isomeric SMILES | CCCC1=NN(C2=C1NC(=NC2=S)C3=C(C=CC(=C3)S(=O)(=O)N4CCNCC4)OCC)C |
PubChem CID | 10140449 |
Molecular Weight | 476.62 |
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Chemical and Physical Properties
Melt Point(°C) | 190-193°C (lit.) |
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