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Dexamethasone 21-phosphate disodium salt - 98%, high purity , Glucocorticoid receptor agonist, CAS No.2392-39-4, Glucocorticoid receptor agonist

≥98%

CAS#: 2392-39-4
Formula: C₂₂H₂₈FNa₂O₈P
Molecular Weight: 516.41
Beilstein Registry Number: 6473066
EC Number: 219-243-0
MDL number: MFCD00079105
PubChem CID: 16961

Item Number

D107196

Grouped product items
SKU	Size	Availability	Price
D107196-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$48.90
D107196-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$54.90
D107196-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$59.90
D107196-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$68.90
D107196-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$124.90
D107196-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$558.90
D107196-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,515.90

Potent glucocorticoid receptor agonist. Dexamethasone prodrug.

Basic Description

Synonyms	DEXAMETHASONE SODIUM PHOSPHATE\|2392-39-4\|Dexamethasone 21-phosphate disodium salt\|Dalalone\|Dexadreson\|Dexagro\|Megacort\|Soldesam\|Dexamethasone disodium phosphate\|55203-24-2\|Decadron phosphate\|Dexabene\|Spersadox\|Decdan\|Solu-Decadron\|Ak-Dex\|Colvasone\|Dexagel
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Potent glucocorticoid receptor agonist and dexamethasone prodrug. Multiple effects on cell survival, cell signaling and gene expression. Anti-inflammatory and immunosupressant. Active in vivo.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Action Type	AGONIST
Mechanism of action	Glucocorticoid receptor agonist
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.

Names and Identifiers

IUPAC Name	disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
INCHI	InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1
InChi Key	PLCQGRYPOISRTQ-FCJDYXGNSA-L
Canonical SMILES	CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
Isomeric SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
WGK Germany	3
RTECS	TU4056000
PubChem CID	16961
Molecular Weight	516.41
Beilstein	6473066

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot Number	Certificate Type	Date	Item
C23111257	Certificate of Analysis	Jan 09, 2023	D107196
C23111274	Certificate of Analysis	Jan 09, 2023	D107196
C23111282	Certificate of Analysis	Jan 09, 2023	D107196
C23111284	Certificate of Analysis	Jan 09, 2023	D107196
C23111289	Certificate of Analysis	Jan 09, 2023	D107196
C23111301	Certificate of Analysis	Jan 09, 2023	D107196
H2429033	Certificate of Analysis	Jan 09, 2023	D107196
L2321189	Certificate of Analysis	Jan 09, 2023	D107196
I2219400	Certificate of Analysis	Sep 29, 2022	D107196
E2213155	Certificate of Analysis	May 21, 2022	D107196
I2219401	Certificate of Analysis	May 21, 2022	D107196
C2212520	Certificate of Analysis	Mar 19, 2022	D107196

Chemical and Physical Properties

Solubility	Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
Sensitivity	Moisture sensitive，heat sensitive
Melt Point(°C)	235 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H351:Suspected of causing cancer H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed H332:Harmful if inhaled H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	TU4056000

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