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Dexamethasone 21-phosphate disodium salt - 10mM in Water, high purity , CAS No.2392-39-4
Potent glucocorticoid receptor agonist. Dexamethasone prodrug.
Basic Description Synonyms DEXAMETHASONE SODIUM PHOSPHATE|2392-39-4|Dexamethasone 21-phosphate disodium salt|Dalalone|Dexadreson|Dexagro|Megacort|Soldesam|Dexamethasone disodium phosphate|55203-24-2|Decadron phosphate|Dexabene|Spersadox|Decdan|Solu-Decadron|Ak-Dex|Colvasone|Dexagel Specifications & Purity 10mM in Water Biochemical and Physiological Mechanisms Potent glucocorticoid receptor agonist and dexamethasone prodrug. Multiple effects on cell survival, cell signaling and gene expression. Anti-inflammatory and immunosupressant. Active in vivo. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.
Names and Identifiers IUPAC Name disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate INCHI InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1 InChi Key PLCQGRYPOISRTQ-FCJDYXGNSA-L Canonical SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] Isomeric SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] WGK Germany 3 RTECS TU4056000 PubChem CID 16961 Molecular Weight 516.41 Beilstein 6473066
Chemical and Physical Properties Sensitivity Moisture sensitive，heat sensitive Melt Point(°C) 235 °C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Danger Hazard Statements H351: Suspected of causing cancer
H373: Causes damage to organs through prolonged or repeated exposure
H302: Harmful if swallowed
H332: Harmful if inhaled
H360: May damage fertility or the unborn child
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
P317: Get emergency medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RTECS TU4056000
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