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Dextrorphan - 97%, high purity , CAS No.125-73-5, Channel blocker of GluN2C

Moligand™
≥97%

CAS#: 125-73-5
Formula: C₁₇H₂₃NO
Molecular Weight: 257.37
PubChem CID: 5360697

Item Number

D609852

Grouped product items
SKU	Size	Availability	Price	Qty
D609852-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$95.90
D609852-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90

View related series

GluN2C Channel blocker

Basic Description

Synonyms	DEXTRORPHAN\|Levorphanol d-form\|125-73-5\|d-3-Hydroxy-N-methylmorphinan\|Dextrorphane\|Dextrorphanum\|Dextro-Dromoran\|D-levorphanol\|(+)-dextrorphan\|CHEBI:29133\|04B7QNO9WS\|Ent-17-methylmorphinan-3-ol\|Ro 1-6794\|(+)-N-Methylmorphinan-3-ol\|(+)-3-Hydroxy-N-methylmo
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of GluN2C
Product Description	Dextrorphan has been studies as an N-methyl-D-aspartate (NMDA) receptor antagonist in Xenopus oocytes and hippocampal neuron cultures. CYP2D6 O-Demethyl metabolite of dextromethorphan

Associated Targets

SLC22A1 Tchem Solute carrier family 22 member 1 0 Activities

Discover Target: SLC22A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SCN1A Tclin Sodium channel protein type 1 subunit alpha 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A4 Tbio UDP-glucuronosyltransferase 1-4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A9 Tbio UDP-glucuronosyltransferase 1-9 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A3 Tbio UDP-glucuronosyltransferase 1-3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A6 Tbio UDP-glucuronosyltransferase 1-6 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A7 Tbio UDP-glucuronosyltransferase 1-7 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B4 Tbio UDP-glucuronosyltransferase 2B4 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT2B17 Tbio UDP-glucuronosyltransferase 2B17 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 0 Activities

Discover Target: GRIN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C 1 Activities

Discover Target: GRIN2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
INCHI	InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1
InChi Key	JAQUASYNZVUNQP-PVAVHDDUSA-N
Canonical SMILES	CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)O
Isomeric SMILES	CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)O
WGK Germany	3
RTECS	QD1832000
PubChem CID	5360697
Molecular Weight	257.37

BindingDB Ligand

50001000

ChEMBL Ligand

CHEMBL1254766

PubChem CID

5360697

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
D2410455	Certificate of Analysis	Mar 29, 2024	D609852
D2410456	Certificate of Analysis	Mar 29, 2024	D609852
D2410457	Certificate of Analysis	Mar 29, 2024	D609852
D2410458	Certificate of Analysis	Mar 29, 2024	D609852

Solubility

saline: soluble(lit.)

Melt Point(°C)

≥195 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	QD1832000
RIDADR	NONHforallmodesoftransport

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