DFMTI - 10mM in DMSO, high purity , CAS No.864864-86-8(DMSO)

  • 10mM in DMSO
Item Number
D655144
Grouped product items
SKUSizeAvailabilityPrice Qty
D655144-1ml
1ml
Available within 8-12 weeks(?)
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$340.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsDFMTI can completely block the rmGlu1 L757V glutamate response.\nIn vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade.\nIn vivo: DFMTI is efficacious in dis
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

DFMTI can completely block the rmGlu1 L757V glutamate response.In vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade.In vivo: DFMTI is efficacious in disrupting prepulse inhibition when dosed orally in rats. DFMTI exhibits a moderate decrease in human potency of approximately 3-fold when compared to rat, exemplified by DFMTI.

IC50& Target:mGluR1

Names and Identifiers

Canonical SMILES O=C(N(C(C)C)C1)C2=C1C=C(C3=C(C)N(C4=CC=C(F)C=C4F)N=N3)C=C2
Molecular Weight 368.38

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