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DFP00173 - 99%, high purity , CAS No.672286-03-2

≥99%

CAS#: 672286-03-2
Formula: C₁₁H₇Cl₂N₃O₃S
Molecular Weight: 332.16
PubChem CID: 2806296

Item Number

D647514

Grouped product items
SKU	Size	Availability	Price
D647514-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
D647514-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
D647514-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$990.90
D647514-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90
D647514-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,250.90

View related series

Aquaporin Membrane Transporter/Ion Channel

Basic Description

Synonyms	DFP00173\|672286-03-2\|1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea\|N-(2,6-dichlorophenyl)-N'-(5-nitro-3-thienyl)urea\|MLS000851390\|CHEMBL1442132\|DTXSID701329723\|HMS2783C13\|AKOS040732960\|CCG-242921\|MS-24996\|SMR000457833\|HY-126073\|CS-0090372
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC 50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC 50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9. In Vitro DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC 50 of ~0.2 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Associated Targets

POLI Tchem DNA polymerase iota 0 Activities

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MBNL1 Tbio Muscleblind-like protein 1 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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CGA Tbio Glycoprotein hormones alpha chain 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Discover Target: NFE2L2

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Names and Identifiers

IUPAC Name	1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea
INCHI	InChI=1S/C11H7Cl2N3O3S/c12-7-2-1-3-8(13)10(7)15-11(17)14-6-4-9(16(18)19)20-5-6/h1-5H,(H2,14,15,17)
InChi Key	AATXXTHMITUAOJ-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C(=C1)Cl)NC(=O)NC2=CSC(=C2)[N+](=O)[O-])Cl
Isomeric SMILES	C1=CC(=C(C(=C1)Cl)NC(=O)NC2=CSC(=C2)[N+](=O)[O-])Cl
Alternate CAS	672286-03-2
PubChem CID	2806296
Molecular Weight	332.16

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