Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Di-tert-butyl dicarbonate - 99%, high purity , CAS No.24424-99-5

  • ≥99%
Item Number
D106159
Grouped product items
SKUSizeAvailabilityPrice Qty
D106159-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$37.90
D106159-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$105.90
D106159-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$369.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET
View related series
Amino protection Deprotection Derivatization Protection Protection and derivatization reagents Tert-butoxycarbonyl (Boc)ation agent

Basic Description

SynonymsDi-tert-butyl dicarbonate|24424-99-5|BOC anhydride|Bis(tert-butoxycarbonyl)oxide|di-tert-Butyl pyrocarbonate|Di-tert-butyldicarbonate|Boc2O|tert-Butoxycarbonyl anhydride|BOC-anhydride|di-t-Butyl dicarbonate|Dicarbonic acid, bis(1,1-dimethylethyl) ester|Di
Specifications & Purity99%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Product Description

Aminomethyl allene was prepared by reaction of Boc propargyl amine with formaldehyde, diisopropylamine and copper bromide as part of a series of Bovine Plasma Amine Oxidase inactivators Protection of alcohols as Boc derivatives via Lewis acid catalysis. Reagent for the introduction of the Boc protecting group. Reagent for the preparation of Boc protected amines. Tris-Boc protected hydrazine allows preparation of Fmoc ester in a chromophoric reagent to monitor solid-phase aldehydes.

Names and Identifiers

IUPAC Name tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate
INCHI InChI=1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3
InChi Key DYHSDKLCOJIUFX-UHFFFAOYSA-N
Canonical SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
Isomeric SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
WGK Germany 3
RTECS HT0230000
PubChem CID 90495
UN Number 2929
Packing Group II
Molecular Weight 218.25
Beilstein 1911173

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

29 results found

Lot NumberCertificate TypeDateItem
G2422545Certificate of AnalysisJul 10, 2024 D106159
G2419498Certificate of AnalysisJul 10, 2024 D106159
G2419464Certificate of AnalysisJul 10, 2024 D106159
F2404260Certificate of AnalysisMay 24, 2024 D106159
F2404259Certificate of AnalysisMay 24, 2024 D106159
D2412167Certificate of AnalysisApr 02, 2024 D106159
D2412165Certificate of AnalysisApr 02, 2024 D106159
D2412166Certificate of AnalysisApr 02, 2024 D106159
A2408447Certificate of AnalysisJan 02, 2024 D106159
A2408446Certificate of AnalysisJan 02, 2024 D106159
A2408448Certificate of AnalysisJan 02, 2024 D106159
A2408449Certificate of AnalysisJan 02, 2024 D106159
L2312367Certificate of AnalysisDec 04, 2023 D106159
L2312366Certificate of AnalysisDec 04, 2023 D106159
H2329733Certificate of AnalysisAug 28, 2023 D106159
E2323401Certificate of AnalysisApr 20, 2023 D106159
G2327142Certificate of AnalysisApr 20, 2023 D106159
E2323426Certificate of AnalysisApr 20, 2023 D106159
E2323406Certificate of AnalysisApr 20, 2023 D106159
B2314234Certificate of AnalysisFeb 02, 2023 D106159
J2219341Certificate of AnalysisSep 14, 2022 D106159
J2219480Certificate of AnalysisSep 14, 2022 D106159
D2313836Certificate of AnalysisSep 14, 2022 D106159
F2221248Certificate of AnalysisJul 03, 2022 D106159
G2216195Certificate of AnalysisJun 15, 2022 D106159
G2216196Certificate of AnalysisJun 15, 2022 D106159
G2216197Certificate of AnalysisJun 15, 2022 D106159
G2216192Certificate of AnalysisJun 15, 2022 D106159
B2226067Certificate of AnalysisJan 24, 2022 D106159

more

Chemical and Physical Properties

SolubilityMiscible with decalin, toluene, carbon tetrachloride, tetrahydrofuran, dioxane, alcohols, acetone, acetonitrile and dimethylformamide. Immiscible with water.
SensitivityHeat sensitive;Hygroscopic;Light sensitive;moisture sensitive
Refractive Index1.409
Flash Point(°F)98.6 °F
Flash Point(°C)37℃
Boil Point(°C)56-57 °C/0.5 mmHg
Melt Point(°C)23°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05,   GHS02
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H318:Causes serious eye damage

H225:Highly Flammable liquid and vapor

H317:May cause an allergic skin reaction

H228:Flammable solid

H226:Flammable liquid and vapor

H330:Fatal if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P320:Specific treatment is urgent (see ... on this label).

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS HT0230000
Class 6.1 (3)

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Di-tert-butyl dicarbonate - 98%, used for , CAS No. 24424-99-5, by Aladdin Scientific
    Di-tert-butyl dicarbonate

    Starting at $34.90

  2. Di-tert-butyl dicarbonate solution
    Di-tert-butyl dicarbonate solution

    Starting at $215.90

  3. Di-tert-butyl dicarbonate solution - 1.0 M in THF, used for , CAS No. 24424-99-5, by Aladdin Scientific
    Di-tert-butyl dicarbonate solution

    Starting at $167.90

  4. Di-tert-butyl dicarbonate - 96%, used for , CAS No. 24424-99-5, by Aladdin Scientific
    Di-tert-butyl dicarbonate

    Starting at $30.90

  5. Di-tert-butyl dicarbonate solution
    Di-tert-butyl dicarbonate solution

    Starting at $215.90

References

1. Hameed P S, Solapure S, Patil V, Henrich PP, Magistrado PA, Bharath S, Murugan K, Viswanath P, Puttur J, Srivastava A et al..  (2015)  Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate..  Nat Commun,  6  (3): (6715).  [PMID:25823686]
2. J S Allen,J Panfili.  (1986-04-01)  Ames Salmonella/mammalian-microsome testing of peptides and peptide synthesis reagents..  Mutation research,  170  ((1-2)): (23-29).  [PMID:3515165]
3. Debmalya Roy,P K Basu,P Raghunathan,S V Eswaran.  (2004-01-28)  Quantitative estimation of the degree of derivatization: an alternative methodology using 1-D and 2-D NMR experiments..  Magnetic resonance in chemistry : MRC,  42  ((1)): (76-80).  [PMID:14745821]
4. Asit K Chakraborti,Sunay V Chankeshwara.  (2006-07-11)  HClO4-SiO2 as a new, highly efficient, inexpensive and reusable catalyst for N-tert-butoxycarbonylation of amines..  Organic & biomolecular chemistry,  4  ((14)): (2769-2771).  [PMID:16826301]
5. Giuseppe Bartoli,Marcella Bosco,Armando Carlone,Renato Dalpozzo,Manuela Locatelli,Paolo Melchiorre,Letizia Sambri.  (2006-12-16)  Alcohols and di-tert-butyl dicarbonate: how the nature of the Lewis acid catalyst may address the reaction to the synthesis of tert-butyl ethers..  The Journal of organic chemistry,  71  ((26)): (9580-9588).  [PMID:17168573]
6. Brandon S Fowler,Peter J Mikochik,Scott J Miller.  (2010-02-18)  Peptide-catalyzed kinetic resolution of formamides and thioformamides as an entry to nonracemic amines..  Journal of the American Chemical Society,  132  ((9)): (2870-2871).  [PMID:20158213]
7. Jason C Green,Sandra Jiménez-Alonso,Eric R Brown,Thomas R R Pettus.  (2011-09-21)  Total synthesis and repudiation of the helianane family..  Organic letters,  13  ((20)): (5500-5503).  [PMID:21928811]
8. Wendell Ho-Tin Law,Kam-Keung Leung,Lawrence Cho-Cheung Lee,Che-Shan Poon,Hua-Wei Liu,Kenneth Kam-Wing Lo.  (2014-03-20)  Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing..  ChemMedChem,  9  ((6)): (1316-1329).  [PMID:24643988]
9. Elena Pérez,Ana Martínez,César Teijón,Jose M Teijón,M Dolores Blanco.  (2014-05-13)  Bioresponsive nanohydrogels based on HEAA and NIPA for poorly soluble drugs delivery..  International journal of pharmaceutics,  470  ((1-2)): (107-119).  [PMID:24813784]
10. Wanyi Tai,Ran Mo,Yue Lu,Tianyue Jiang,Zhen Gu.  (2014-05-31)  Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs..  Biomaterials,  35  ((25)): (7194-7203).  [PMID:24875756]
11. Laura M Thoma,Blaise R Boles,Kenichi Kuroda.  (2014-07-11)  Cationic methacrylate polymers as topical antimicrobial agents against Staphylococcus aureus nasal colonization..  Biomacromolecules,  15  ((8)): (2933-2943).  [PMID:25010735]
12. Hans Peter Reisenauer,J Philipp Wagner,Peter R Schreiner.  (2014-09-10)  Gas-phase preparation of carbonic acid and its monomethyl ester..  Angewandte Chemie (International ed. in English),  53  ((44)): (11766-11771).  [PMID:25196920]
13. Diana Vivian,James E Polli.  (2014-09-16)  Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver..  International journal of pharmaceutics,  475  ((1-2)): (597-604).  [PMID:25219859]
14. Sasmita Mohapatra,Smruti Ranjan Rout,Rajan Narayan,Tapas K Maiti.  (2014-09-17)  Multifunctional mesoporous hollow silica nanocapsules for targeted co-delivery of cisplatin-pemetrexed and MR imaging..  Dalton transactions (Cambridge, England : 2003),  43  ((42)): (15841-15850).  [PMID:25224136]
15. Kohji Abe,Nozomi Takai,Kazumi Fukumoto,Natsumi Imamoto,Misato Tonomura,Miwa Ito,Naoki Kanegawa,Katsunori Sakai,Kenji Morimoto,Kenichiro Todoroki,Osamu Inoue.  (2014-09-18)  In vivo imaging of reactive oxygen species in mouse brain by using [3H]hydromethidine as a potential radical trapping radiotracer..  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,  34  ((12)): (1907-1913).  [PMID:25227606]
16. Qingqing Zhang,Ming Zhou.  (2014-10-05)  A profluorescent ratiometric probe for intracellular pH imaging..  Talanta,  131  (666-671).  [PMID:25281157]
17. Sevnur Serim,Philipp Baer,Steven H L Verhelst.  (2015-01-03)  Mixed alkyl aryl phosphonate esters as quenched fluorescent activity-based probes for serine proteases..  Organic & biomolecular chemistry,  13  ((8)): (2293-2299).  [PMID:25553959]
18. Daniel G Abebe,Rima Kandil,Teresa Kraus,Maha Elsayed,Olivia M Merkel,Tomoko Fujiwara.  (2015-02-04)  Three-Layered Biodegradable Micelles Prepared by Two-Step Self-Assembly of PLA-PEI-PLA and PLA-PEG-PLA Triblock Copolymers as Efficient Gene Delivery System..  Macromolecular bioscience,  15  ((5)): (698-711).  [PMID:25644720]
19. Jun-Qing Situ,Yi-Qing Ye,Xiu-Liang Zhu,Ri-Sheng Yu,Jian You,Hong Yuan,Fu-Qiang Hu,Yong-Zhong Du.  (2015-02-06)  Specific targeting of A54 homing peptide-functionalized dextran-g-poly(lactic-co-glycolic acid) micelles to tumor cells..  International journal of nanomedicine,  10  (665-675).  [PMID:25653517]
20. Pavla Simerska,Zyta Maria Ziora,Vincent Fagan,Daryn Goodwin,Farrah Edrous,Istvan Toth.  (2015-03-20)  Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system..  Drug delivery and translational research,  4  ((3)): (246-255).  [PMID:25786879]
21. Yi Liu,Hongyu Piao,Ying Gao,Caihong Xu,Ye Tian,Lihong Wang,Jinwen Liu,Bo Tang,Meijuan Zou,Gang Cheng.  (2015-04-08)  Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity..  International journal of nanomedicine,  10  (2295-2311).  [PMID:25848251]
22. Elena Geromichalou,Nisar Sayyad,Eleni Kyriakou,Alexandra V Chatzikonstantinou,Efstathia Giannopoulou,Norbert Vrbjar,Haralabos P Kalofonos,Haralambos Stamatis,Andreas G Tzakos.  (2015-04-16)  Regioselective chemical and rapid enzymatic synthesis of a novel redox – Antiproliferative molecular hybrid..  European journal of medicinal chemistry,  96  (47-57).  [PMID:25874330]
23. Tadla Vijeetha,Marrapu Balakrishna,Mallampalli Sri Lakshmi Karuna,Bhamidipati Venkata Surya Koppeswara Rao,Rachapudi Badari Narayana Prasad,Koochana Pranay Kumar,Upadyaula Surya Narayana Murthy.  (2015-05-23)  Synthesis and Anti-microbial Activity of Novel Phosphatidylethanolamine-N-amino Acid Derivatives..  Journal of oleo science,  64  ((7)): (705-712).  [PMID:25994558]
24. Tommy Siu-Ming Tang,Alex Man-Hei Yip,Kenneth Yin Zhang,Hua-Wei Liu,Po Lam Wu,King Fai Li,Kok Wai Cheah,Kenneth Kam-Wing Lo.  (2015-06-23)  Bioorthogonal Labeling, Bioimaging, and Photocytotoxicity Studies of Phosphorescent Ruthenium(II) Polypyridine Dibenzocyclooctyne Complexes..  Chemistry (Weinheim an der Bergstrasse, Germany),  21  ((30)): (10729-10740).  [PMID:26096074]
25. Lucia Cenci,Erika Andreetto,Ambra Vestri,Michele Bovi,Mario Barozzi,Erica Iacob,Mirko Busato,Annalisa Castagna,Domenico Girelli,Alessandra Maria Bossi.  (2015-08-28)  Surface plasmon resonance based on molecularly imprinted nanoparticles for the picomolar detection of the iron regulating hormone Hepcidin-25..  Journal of nanobiotechnology,  13  (51-51).  [PMID:26311037]
26. Ashish Punia,Kevin Lee,Edward He,Sumit Mukherjee,Andrew Mancuso,Probal Banerjee,Nan-Loh Yang.  (2015-10-17)  Effect of Relative Arrangement of Cationic and Lipophilic Moieties on Hemolytic and Antibacterial Activities of PEGylated Polyacrylates..  International journal of molecular sciences,  16  ((10)): (23867-23880).  [PMID:26473831]
27. Massimiliano Clamer,Toma Tebaldi,Fabio Lauria,Paola Bernabò,Rodolfo F Gómez-Biagi,Marta Marchioretto,Divya T Kandala,Luca Minati,Elena Perenthaler,Daniele Gubert,Laura Pasquardini,Graziano Guella,Ewout J N Groen,Thomas H Gillingwater,Alessandro Quattrone,Gabriella Viero.  (2018-10-26)  Active Ribosome Profiling with RiboLace..  Cell reports,  25  ((4)): (1097-1108).  [PMID:30355487]
28. Simon K Shannon,George Barany.  (2004-07-03)  4-(9-fluorenylmethyloxycarbonyl)phenylhydrazine (FmPH): a new chromophoric reagent for quantitative monitoring of solid-phase aldehydes(1-3)..  The Journal of organic chemistry,  69  ((14)): (4586-4594).  [PMID:15230579]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.