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Di-tert-butyl dicarbonate solution - 2 M in methylene chloride, high purity , CAS No.24424-99-5

  • 2 M in methylene chloride
Item Number
D432365
Grouped product items
SKUSizeAvailabilityPrice Qty
D432365-100ml
100ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$215.90
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Basic Description

SynonymsDi-tert-butyl dicarbonate|24424-99-5|BOC anhydride|Bis(tert-butoxycarbonyl)oxide|di-tert-Butyl pyrocarbonate|Di-tert-butyldicarbonate|Boc2O|tert-Butoxycarbonyl anhydride|BOC-anhydride|di-t-Butyl dicarbonate|Dicarbonic acid, bis(1,1-dimethylethyl) ester|Di
Specifications & Purity2 M in methylene chloride

Names and Identifiers

IUPAC Name tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate
INCHI InChI=1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3
InChi Key DYHSDKLCOJIUFX-UHFFFAOYSA-N
Canonical SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
Isomeric SMILES CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
WGK Germany 3
RTECS HT0230000
PubChem CID 90495
UN Number 2929
Packing Group II
Molecular Weight 218.25
Beilstein 1911173

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Refractive Index1.409
Flash Point(°F)98.6 °F
Flash Point(°C)37℃
Boil Point(°C)56-57 °C/0.5 mmHg
Melt Point(°C)23°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05,   GHS02
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H318:Causes serious eye damage

H225:Highly Flammable liquid and vapor

H317:May cause an allergic skin reaction

H228:Flammable solid

H226:Flammable liquid and vapor

H330:Fatal if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P320:Specific treatment is urgent (see ... on this label).

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS HT0230000
Class 6.1 (3)

Related Documents

 SDS

 Specification Sheet

References

1. Hameed P S, Solapure S, Patil V, Henrich PP, Magistrado PA, Bharath S, Murugan K, Viswanath P, Puttur J, Srivastava A et al..  (2015)  Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate..  Nat Commun,  6  (3): (6715).  [PMID:25823686]
2. J S Allen,J Panfili.  (1986-04-01)  Ames Salmonella/mammalian-microsome testing of peptides and peptide synthesis reagents..  Mutation research,  170  ((1-2)): (23-29).  [PMID:3515165]
3. Debmalya Roy,P K Basu,P Raghunathan,S V Eswaran.  (2004-01-28)  Quantitative estimation of the degree of derivatization: an alternative methodology using 1-D and 2-D NMR experiments..  Magnetic resonance in chemistry : MRC,  42  ((1)): (76-80).  [PMID:14745821]
4. Asit K Chakraborti,Sunay V Chankeshwara.  (2006-07-11)  HClO4-SiO2 as a new, highly efficient, inexpensive and reusable catalyst for N-tert-butoxycarbonylation of amines..  Organic & biomolecular chemistry,  4  ((14)): (2769-2771).  [PMID:16826301]
5. Giuseppe Bartoli,Marcella Bosco,Armando Carlone,Renato Dalpozzo,Manuela Locatelli,Paolo Melchiorre,Letizia Sambri.  (2006-12-16)  Alcohols and di-tert-butyl dicarbonate: how the nature of the Lewis acid catalyst may address the reaction to the synthesis of tert-butyl ethers..  The Journal of organic chemistry,  71  ((26)): (9580-9588).  [PMID:17168573]
6. Brandon S Fowler,Peter J Mikochik,Scott J Miller.  (2010-02-18)  Peptide-catalyzed kinetic resolution of formamides and thioformamides as an entry to nonracemic amines..  Journal of the American Chemical Society,  132  ((9)): (2870-2871).  [PMID:20158213]
7. Jason C Green,Sandra Jiménez-Alonso,Eric R Brown,Thomas R R Pettus.  (2011-09-21)  Total synthesis and repudiation of the helianane family..  Organic letters,  13  ((20)): (5500-5503).  [PMID:21928811]
8. Wendell Ho-Tin Law,Kam-Keung Leung,Lawrence Cho-Cheung Lee,Che-Shan Poon,Hua-Wei Liu,Kenneth Kam-Wing Lo.  (2014-03-20)  Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing..  ChemMedChem,  9  ((6)): (1316-1329).  [PMID:24643988]
9. Elena Pérez,Ana Martínez,César Teijón,Jose M Teijón,M Dolores Blanco.  (2014-05-13)  Bioresponsive nanohydrogels based on HEAA and NIPA for poorly soluble drugs delivery..  International journal of pharmaceutics,  470  ((1-2)): (107-119).  [PMID:24813784]
10. Wanyi Tai,Ran Mo,Yue Lu,Tianyue Jiang,Zhen Gu.  (2014-05-31)  Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs..  Biomaterials,  35  ((25)): (7194-7203).  [PMID:24875756]
11. Laura M Thoma,Blaise R Boles,Kenichi Kuroda.  (2014-07-11)  Cationic methacrylate polymers as topical antimicrobial agents against Staphylococcus aureus nasal colonization..  Biomacromolecules,  15  ((8)): (2933-2943).  [PMID:25010735]
12. Hans Peter Reisenauer,J Philipp Wagner,Peter R Schreiner.  (2014-09-10)  Gas-phase preparation of carbonic acid and its monomethyl ester..  Angewandte Chemie (International ed. in English),  53  ((44)): (11766-11771).  [PMID:25196920]
13. Diana Vivian,James E Polli.  (2014-09-16)  Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver..  International journal of pharmaceutics,  475  ((1-2)): (597-604).  [PMID:25219859]
14. Sasmita Mohapatra,Smruti Ranjan Rout,Rajan Narayan,Tapas K Maiti.  (2014-09-17)  Multifunctional mesoporous hollow silica nanocapsules for targeted co-delivery of cisplatin-pemetrexed and MR imaging..  Dalton transactions (Cambridge, England : 2003),  43  ((42)): (15841-15850).  [PMID:25224136]
15. Kohji Abe,Nozomi Takai,Kazumi Fukumoto,Natsumi Imamoto,Misato Tonomura,Miwa Ito,Naoki Kanegawa,Katsunori Sakai,Kenji Morimoto,Kenichiro Todoroki,Osamu Inoue.  (2014-09-18)  In vivo imaging of reactive oxygen species in mouse brain by using [3H]hydromethidine as a potential radical trapping radiotracer..  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,  34  ((12)): (1907-1913).  [PMID:25227606]
16. Qingqing Zhang,Ming Zhou.  (2014-10-05)  A profluorescent ratiometric probe for intracellular pH imaging..  Talanta,  131  (666-671).  [PMID:25281157]
17. Sevnur Serim,Philipp Baer,Steven H L Verhelst.  (2015-01-03)  Mixed alkyl aryl phosphonate esters as quenched fluorescent activity-based probes for serine proteases..  Organic & biomolecular chemistry,  13  ((8)): (2293-2299).  [PMID:25553959]
18. Daniel G Abebe,Rima Kandil,Teresa Kraus,Maha Elsayed,Olivia M Merkel,Tomoko Fujiwara.  (2015-02-04)  Three-Layered Biodegradable Micelles Prepared by Two-Step Self-Assembly of PLA-PEI-PLA and PLA-PEG-PLA Triblock Copolymers as Efficient Gene Delivery System..  Macromolecular bioscience,  15  ((5)): (698-711).  [PMID:25644720]
19. Jun-Qing Situ,Yi-Qing Ye,Xiu-Liang Zhu,Ri-Sheng Yu,Jian You,Hong Yuan,Fu-Qiang Hu,Yong-Zhong Du.  (2015-02-06)  Specific targeting of A54 homing peptide-functionalized dextran-g-poly(lactic-co-glycolic acid) micelles to tumor cells..  International journal of nanomedicine,  10  (665-675).  [PMID:25653517]
20. Pavla Simerska,Zyta Maria Ziora,Vincent Fagan,Daryn Goodwin,Farrah Edrous,Istvan Toth.  (2015-03-20)  Design, synthesis and characterisation of mannosylated ovalbumin lipid core peptide self-adjuvanting vaccine delivery system..  Drug delivery and translational research,  4  ((3)): (246-255).  [PMID:25786879]
21. Yi Liu,Hongyu Piao,Ying Gao,Caihong Xu,Ye Tian,Lihong Wang,Jinwen Liu,Bo Tang,Meijuan Zou,Gang Cheng.  (2015-04-08)  Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity..  International journal of nanomedicine,  10  (2295-2311).  [PMID:25848251]
22. Elena Geromichalou,Nisar Sayyad,Eleni Kyriakou,Alexandra V Chatzikonstantinou,Efstathia Giannopoulou,Norbert Vrbjar,Haralabos P Kalofonos,Haralambos Stamatis,Andreas G Tzakos.  (2015-04-16)  Regioselective chemical and rapid enzymatic synthesis of a novel redox – Antiproliferative molecular hybrid..  European journal of medicinal chemistry,  96  (47-57).  [PMID:25874330]
23. Tadla Vijeetha,Marrapu Balakrishna,Mallampalli Sri Lakshmi Karuna,Bhamidipati Venkata Surya Koppeswara Rao,Rachapudi Badari Narayana Prasad,Koochana Pranay Kumar,Upadyaula Surya Narayana Murthy.  (2015-05-23)  Synthesis and Anti-microbial Activity of Novel Phosphatidylethanolamine-N-amino Acid Derivatives..  Journal of oleo science,  64  ((7)): (705-712).  [PMID:25994558]
24. Tommy Siu-Ming Tang,Alex Man-Hei Yip,Kenneth Yin Zhang,Hua-Wei Liu,Po Lam Wu,King Fai Li,Kok Wai Cheah,Kenneth Kam-Wing Lo.  (2015-06-23)  Bioorthogonal Labeling, Bioimaging, and Photocytotoxicity Studies of Phosphorescent Ruthenium(II) Polypyridine Dibenzocyclooctyne Complexes..  Chemistry (Weinheim an der Bergstrasse, Germany),  21  ((30)): (10729-10740).  [PMID:26096074]
25. Lucia Cenci,Erika Andreetto,Ambra Vestri,Michele Bovi,Mario Barozzi,Erica Iacob,Mirko Busato,Annalisa Castagna,Domenico Girelli,Alessandra Maria Bossi.  (2015-08-28)  Surface plasmon resonance based on molecularly imprinted nanoparticles for the picomolar detection of the iron regulating hormone Hepcidin-25..  Journal of nanobiotechnology,  13  (51-51).  [PMID:26311037]
26. Ashish Punia,Kevin Lee,Edward He,Sumit Mukherjee,Andrew Mancuso,Probal Banerjee,Nan-Loh Yang.  (2015-10-17)  Effect of Relative Arrangement of Cationic and Lipophilic Moieties on Hemolytic and Antibacterial Activities of PEGylated Polyacrylates..  International journal of molecular sciences,  16  ((10)): (23867-23880).  [PMID:26473831]

Solution Calculators

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