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Diallyl N,N-diisopropylphosphoramidite - ≥90%, high purity , CAS No.126429-21-8

  • ≥90%
Item Number
D332864
Grouped product items
SKUSizeAvailabilityPrice Qty
D332864-250mg
250mg
5
$78.90
D332864-1g
1g
2
$240.90

Basic Description

SynonymsDiallyl N,N-di isopropyl phosphoramidite | DTXSID20405573 | N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine | di-allyl-N,N-diisopropylphosphoramidite | DIALLYLN,N-DIISOPROPYLPHOSPHORAMIDITE | FT-0756764 | AKOS015895011 | J-005381 | SCHEMBL386395
Specifications & Purity≥90%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Precursor involved in the synthesis of pharmacologically active molecules including:
Selective orally active S1P1 agonists
Water-soluble prodrugs of triazole CS-758 with antifungal activity
Fostriecin analogs as antitumor agents

Reactant involved in:
Phosphitylation of alcohols
Deallylation for the synthesis of nucleoside phosphoramidite
Posphitylation and stereoselective Pudovik rearrangement
Diallyl N,N-diisopropylphosphoramidite may be employed as phophorylating reagent in the following studies:
Preparation of peptide substrates.
Preparation of rhodamine dyes with phosphorylated CH2OH sites.
Synthesis of 3-[4-(bis-allyloxy-phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester.

AI Insight

Names and Identifiers

Pubchem Sid504763106
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763106
IUPAC Name N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine
INCHI InChI=1S/C12H24NO2P/c1-7-9-14-16(15-10-8-2)13(11(3)4)12(5)6/h7-8,11-12H,1-2,9-10H2,3-6H3
InChi Key QBLCHHSGJTUNSJ-UHFFFAOYSA-N
Canonical SMILES CC(C)N(C(C)C)P(OCC=C)OCC=C
Isomeric SMILES CC(C)N(C(C)C)P(OCC=C)OCC=C
WGK Germany 3
PubChem CID 4686855
UN Number 1993
Packing Group III
Molecular Weight 245.3
Beilstein 4383514

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
L2209570Certificate of AnalysisOct 28, 2022 D332864
L2209644Certificate of AnalysisOct 28, 2022 D332864

Chemical and Physical Properties

Refractive Indexn20D1.46 (lit.)
Flash Point(°F)89.6 °F
Flash Point(°C)32 °C
Boil Point(°C)130° C (lit.)
Melt Point(°C)25.69° C (Predicted)
Molecular Weight245.300 g/mol
XLogP33.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count9
Exact Mass245.154 Da
Monoisotopic Mass245.154 Da
Topological Polar Surface Area21.700 Ų
Heavy Atom Count16
Formal Charge0
Complexity187.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1

Safety and Hazards(GHS)

Pictogram(s) GHS07,   GHS02
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H226:Flammable liquid and vapor

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Class 3
RIDADR UN1993C3/PGIII

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