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Diallyl N,N-diisopropylphosphoramidite - ≥90%, high purity , CAS No.126429-21-8

  • ≥90%
Item Number
D332864
Grouped product items
SKUSizeAvailabilityPrice Qty
D332864-250mg
250mg
In stock
$78.90
D332864-1g
1g
In stock
$240.90

Basic Description

Synonyms126429-21-8|Diallyl N,N-diisopropylphosphoramidite|diallyl diisopropylphosphoramidite|N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine|Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester|bis(allyloxy)(diisopropylamino)phosphine|
Specifications & Purity≥90%
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Precursor involved in the synthesis of pharmacologically active molecules including:
Selective orally active S1P1 agonists
Water-soluble prodrugs of triazole CS-758 with antifungal activity
Fostriecin analogs as antitumor agents

Reactant involved in:
Phosphitylation of alcohols
Deallylation for the synthesis of nucleoside phosphoramidite
Posphitylation and stereoselective Pudovik rearrangement
Diallyl N,N-diisopropylphosphoramidite may be employed as phophorylating reagent in the following studies:
Preparation of peptide substrates.
Preparation of rhodamine dyes with phosphorylated CH2OH sites.
Synthesis of 3-[4-(bis-allyloxy-phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester.

Names and Identifiers

IUPAC Name N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine
INCHI InChI=1S/C12H24NO2P/c1-7-9-14-16(15-10-8-2)13(11(3)4)12(5)6/h7-8,11-12H,1-2,9-10H2,3-6H3
InChi Key QBLCHHSGJTUNSJ-UHFFFAOYSA-N
Canonical SMILES CC(C)N(C(C)C)P(OCC=C)OCC=C
Isomeric SMILES CC(C)N(C(C)C)P(OCC=C)OCC=C
WGK Germany 3
PubChem CID 4686855
UN Number 1993
Packing Group III
Molecular Weight 245.3
Beilstein 4383514

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
L2209570Certificate of AnalysisOct 28, 2022 D332864
L2209644Certificate of AnalysisOct 28, 2022 D332864

Chemical and Physical Properties

Refractive Indexn20D1.46 (lit.)
Flash Point(°F)89.6 °F
Flash Point(°C)32 °C
Boil Point(°C)130° C (lit.)
Melt Point(°C)25.69° C (Predicted)

Safety and Hazards(GHS)

Pictogram(s) GHS07,   GHS02
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H226:Flammable liquid and vapor

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Class 3
RIDADR UN1993C3/PGIII

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