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Diaplasinin - 10mM in DMSO, high purity , CAS No.481631-45-2(DMSO)

  • 10mM in DMSO
Item Number
D656435
Grouped product items
SKUSizeAvailabilityPrice Qty
D656435-1ml
1ml
Available within 8-12 weeks(?)
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$176.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsDiaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295u2003nm. Antithrombotic efficacy.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.

In Vitro

PAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) activities in the presence of PAI-1 (IC 50 values, 157 and 87 nM, respectively). PAI-749 quenches the fluorescence (Fl) of fluorophore-tagged PAI-1 (PAI-NBD119) with the apparent K d of 254 nM) and the IC 50 of 140 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Names and Identifiers

Canonical SMILES CCCCCC1=C(N(C2=C1C=CC=C2)CC3=CC=CC=C3)C4=CC=C5C=C(C=CC5=C4)OCC6=NN=NN6
Molecular Weight 501.62

Certificates

C of A & Other Certificates

Related Documents

Solution Calculators