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Difluoroacetic Acid - 98%, high purity , CAS No.381-73-7

≥98%

CAS#: 381-73-7
Formula: C₂H₂F₂O₂
Molecular Weight: 96.03
Beilstein Registry Number: 1098588
EC Number: 206-839-0
MDL number: MFCD00004220
PubChem CID: 9788

Item Number

D102056

Grouped product items
SKU	Size	Availability	Price
D102056-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$43.90
D102056-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$124.90
D102056-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$448.90
D102056-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,016.90

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Organic acids

Basic Description

Synonyms	DIFLUOROACETIC ACID\|381-73-7\|2,2-Difluoroacetic acid\|Acetic acid, difluoro-\|Difluoressigsaeure\|ZQK1C95K3N\|Acetic acid, 2,2-difluoro-\|CHEBI:23716\|1,1-difluoroacetic acid\|C2H2F2O2\|EINECS 206-839-0\|UNII-ZQK1C95K3N\|BRN 1098588\|AI3-28548\|difluoracetic acid\|Dif
Specifications & Purity	≥98%
Storage Temp	Argon charged
Shipped In	Normal

Names and Identifiers

IUPAC Name	2,2-difluoroacetic acid
INCHI	InChI=1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)
InChi Key	PBWZKZYHONABLN-UHFFFAOYSA-N
Canonical SMILES	C(C(=O)O)(F)F
Isomeric SMILES	C(C(=O)O)(F)F
WGK Germany	3
RTECS	AG9900000
PubChem CID	9788
UN Number	3265
Molecular Weight	96.03
Beilstein	1098588
Reaxy-Rn	1098588

Certificates

Certificate of Analysis(COA)

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10 results found

Lot Number	Certificate Type	Date	Item
K1926159	Certificate of Analysis	Sep 12, 2023	D102056
J2327118	Certificate of Analysis	Aug 10, 2023	D102056
J2327119	Certificate of Analysis	Aug 10, 2023	D102056
G2319333	Certificate of Analysis	Dec 17, 2022	D102056
G2319359	Certificate of Analysis	Dec 17, 2022	D102056
G2319362	Certificate of Analysis	Dec 17, 2022	D102056
B1928103	Certificate of Analysis	Dec 12, 2022	D102056
A2214407	Certificate of Analysis	Dec 24, 2021	D102056
A2214419	Certificate of Analysis	Dec 24, 2021	D102056
A2214420	Certificate of Analysis	Dec 24, 2021	D102056

Solubility

Solubility in water: Completely miscible

Sensitivity

Moisture sensitive.

Refractive Index

1.344

Flash Point(°F)

172.4 °F

Flash Point(°C)

78 °C

Boil Point(°C)

132-134°C

Melt Point(°C)

-1°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	3
RTECS	AG9900000
Reaxy-Rn	1098588

References

1. J N Commandeur,J P Brakenhoff,F J De Kanter,N P Vermeulen. (1988-12-01) Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms.. Biochemical pharmacology, 37 ((23)): (4495-4504). [PMID:3202890]
2. J M Dalstein,G Ribes,P Campo,M M Loubatières-Mariani. (1980-01-01) [Hypolactatemic effect of sodium difluoroacetate].. Comptes rendus des seances de la Societe de biologie et de ses filiales, 174 ((5)): (821-825). [PMID:6449260]
3. Hoffman B M Lantum,Raymond B Baggs,Daria M Krenitsky,M W Anders. (2002-11-21) Nephrotoxicity of chlorofluoroacetic acid in rats.. Toxicological sciences : an official journal of the Society of Toxicology, 70 ((2)): (261-268). [PMID:12441371]
4. William K Hagmann. (2008-06-24) The many roles for fluorine in medicinal chemistry.. Journal of medicinal chemistry, 51 ((15)): (4359-4369). [PMID:18570365]
5. Youngwook Park,Sunghwan Shin,Heon Kang. (2018-07-13) Entropy-Driven Spontaneous Reaction in Cryogenic Ice: Dissociation of Fluoroacetic Acids.. The journal of physical chemistry letters, 9 ((15)): (4282-4286). [PMID:30001139]
6. Roberto Morales-Cerrada, Christophe Fliedel, Jean-Claude Daran, Florence Gayet, Vincent Ladmiral, Bruno Améduri, Rinaldo Poli,. (2018-09-20) Fluoroalkyl Radical Generation by Homolytic Bond Dissociation in Pentacarbonylmanganese Derivatives.. Chemistry (Weinheim an der Bergstrasse, Germany), 25 ((1)): ( 296-308 ). [PMID:30230633]
7. Tse-Hong Chen,Yun Yang,Zhaorui Zhang,Cexiong Fu,Qunying Zhang,Jon D Williams,Mary J Wirth. (2019-01-22) Native Reversed-Phase Liquid Chromatography: A Technique for LCMS of Intact Antibody-Drug Conjugates.. Analytical chemistry, 91 ((4)): (2805-2812). [PMID:30661356]
8. Ute Dorgerloh,Roland Becker,Melanie Kaiser. (2019-03-17) Evidence for the Formation of Difluoroacetic Acid in Chlorofluorocarbon-Contaminated Ground Water.. Molecules (Basel, Switzerland), 24 ((6)): [PMID:30875997]
9. N Illy,J M Dalstein,P Campo,M M Loubatières-Mariani. (1981-01-01) [Effect of sodium difluoroacetate on retinal lactate levels in diabetic rats].. Comptes rendus des seances de la Societe de biologie et de ses filiales, 175 ((2)): (242-246). [PMID:6454472]
10. P D Swartz,A M Richard. (2002-01-05) Use of structure-activity relationships for probing biochemical mechanisms: glutathione transferase zeta conjugation of haloacids.. Advances in experimental medicine and biology, 500 (23-31). [PMID:11764943]
11. Gaëlle Blond,Thierry Billard,Bernard R Langlois. (2002-12-20) Generation and use of an equivalent of difluoroacetamide or difluoroacetate anions.. Chemistry (Weinheim an der Bergstrasse, Germany), 8 ((13)): (2917-2922). [PMID:12489220]
12. Brian M Wagner,Stephanie A Schuster,Barry E Boyes,Taylor J Shields,William L Miles,Mark J Haynes,Robert E Moran,Joseph J Kirkland,Mark R Schure. (2017-02-19) Superficially porous particles with 1000Å pores for large biomolecule high performance liquid chromatography and polymer size exclusion chromatography.. Journal of chromatography. A, 1489 (75-85). [PMID:28213987]
13. Yingqi Mi,Wenqiang Tan,Jingjing Zhang,Lijie Wei,Yuan Chen,Qing Li,Fang Dong,Zhanyong Guo. (2018-09-08) Synthesis, Characterization, and Antifungal Property of Hydroxypropyltrimethyl Ammonium Chitosan Halogenated Acetates.. Marine drugs, 16 ((9)): [PMID:30189609]

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