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Dihydroethidium - 95%, high purity , CAS No.104821-25-2

  • ≥95%
Item Number
D113494
Grouped product items
SKUSizeAvailabilityPrice Qty
D113494-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$41.90
D113494-10mg
10mg
In stock
$64.90
D113494-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$146.90
D113494-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$526.90

Discover Dihydroethidium by Aladdin Scientific in 95% for only $41.90. Available - in Ligands at Aladdin Scientific. Cell-permeable blue fluorescent dye. Redox indicator. Tags: .

Basic Description

SynonymsDihydroethidium|104821-25-2|Hydroethidine|5-ethyl-6-phenyl-5,6-dihydrophenanthridine-3,8-diamine|PD-MY 003|5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine|5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine|3pm1|Dihydroethidium, >=95%|Hydroethidine;PD-M
Specifications & Purity95%
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
Product Description

Hydroethidine operates effectively as a probe for measurement of reactive oxygen species. The dye enters cells freely and is dehydrogenated to ethidium bromide. The probe has been used extensively with NK cell and as a vital dye for identification of proliferation and hypoxic cells in tumors. Studies have been performed using neutrophils and endothelial cells as well as HL60 cells and macrophages. A major advantage of this probe is its ability to distinguish between superoxide and H2O2. Fluorescence emission occurs at around 600 nm.
Redox indicator. Blue fluorescence until oxidized to ethidium

Names and Identifiers

IUPAC Name 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine
INCHI InChI=1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3
InChi Key XYJODUBPWNZLML-UHFFFAOYSA-N
Canonical SMILES CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4
Isomeric SMILES CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4
WGK Germany 3
PubChem CID 128682
Molecular Weight 315.41
Beilstein 5107482

Certificates

Certificate of Analysis(COA)

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11 results found

Lot NumberCertificate TypeDateItem
K2320323Certificate of AnalysisOct 17, 2023 D113494
K2320352Certificate of AnalysisOct 17, 2023 D113494
G2412054Certificate of AnalysisSep 29, 2022 D113494
K2212178Certificate of AnalysisSep 29, 2022 D113494
K2212179Certificate of AnalysisSep 29, 2022 D113494
K2212180Certificate of AnalysisSep 29, 2022 D113494
G2219366Certificate of AnalysisJun 14, 2022 D113494
G2219367Certificate of AnalysisJun 14, 2022 D113494
G2219368Certificate of AnalysisJun 14, 2022 D113494
I2222446Certificate of AnalysisJun 14, 2022 D113494
L2320012Certificate of AnalysisJun 14, 2022 D113494

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Chemical and Physical Properties

SensitivityAir sensitive.Light sensitive.

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

References

1. Upadhyaya G et al..  (2021)  A rice R2R3-MYB (OsC1) transcriptional regulator improves oxidative stress tolerance by modulating anthocyanin biosynthesis..  Physiol Plant,  173  (4): (2334-2349).  [PMID:34625959]
2. Yang Y et al..  (2022)  Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis..  Front Pharmacol,  13  (1037151).  [PMID:36483733]
3. Halder T et al..  (2018)  Dehydrins Impart Protection against Oxidative Stress in Transgenic Tobacco Plants..  Front Plant Sci,  (136).  [PMID:29491874]
4. Muto J et al..  (2023)  Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21..  Commun Biol,  (13).  [PMID:36609486]
5. Zeng X et al..  (2020)  Phoenixin-20 Ameliorates Lipopolysaccharide-Induced Activation of Microglial NLRP3 Inflammasome..  Neurotox Res,  38  (3): (785-792).  [PMID:32651843]

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