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Ligand-gated ion channels
Acid-sensing (proton-gated) ion channels (ASICs)
diminazene , CAS No.D609902, Channel blocker of ASIC1;Channel blocker of ASIC2;Channel blocker of ASIC3

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diminazene , CAS No.D609902, Channel blocker of ASIC1;Channel blocker of ASIC2;Channel blocker of ASIC3

Moligand™

PubChem CID: 2354

Item Number

D609902

Grouped product items
SKU	Size	Availability	Price	Qty
D609902-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D609902-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

ASIC1 Channel blocker ASIC2 Channel blocker ASIC3 Channel blocker

Basic Description

Synonyms	DIMINAZENE\|536-71-0\|berenil\|4,4'-(Diazoamino)benzamidine\|Diminazenum\|Diminazeno\|Azidin\|DIMINAZEN\|4,4'-(1-Triazene-1,3-diyl)bis-benzenecarboximidamide\|Diminazene [INN]\|4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide\|CHEBI:81724\|Diminazene [WHO-DD]\|Benzenecarbox
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of ASIC1;Channel blocker of ASIC2;Channel blocker of ASIC3

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FURIN Tchem Furin 0 Activities

Discover Target: FURIN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SAT1 Tbio Diamine acetyltransferase 1 0 Activities

Discover Target: SAT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CTSB Tchem Cathepsin B 0 Activities

Discover Target: CTSB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AOC1 Tchem Amiloride-sensitive amine oxidase [copper-containing] 1 Activities

Discover Target: AOC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC3 Tchem Acid-sensing ion channel 3 1 Activities

Discover Target: ASIC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC1 Tchem Acid-sensing ion channel 1 1 Activities

Discover Target: ASIC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ASIC2 Tchem Acid-sensing ion channel 2 1 Activities

Discover Target: ASIC2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

INCHI	InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)
InChi Key	XNYZHCFCZNMTFY-UHFFFAOYSA-N
Canonical SMILES	NC(=N)c1ccc(cc1)NN=Nc1ccc(cc1)C(=N)N
Isomeric SMILES	C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N
PubChem CID	2354

Database links

PubChem CID	2354
ChEMBL Ligand	CHEMBL35241
BindingDB Ligand	50000999
DrugBank Ligand	DB03608
RCSB PDB Ligand	BRN

Certificates

Certificate of Analysis(COA)

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Related Documents

Specification Sheet

References

1. Kuriakose S, Uzonna JE. (2014) Diminazene aceturate (Berenil), a new use for an old compound?. Int Immunopharmacol, 21 (2): (342-5). [PMID:24893117]

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