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Dioscin - ≥95% (HPLC), high purity , CAS No.19057-60-4

  • Moligand™
  • ≥95%(HPLC)
Item Number
D463729
Grouped product items
SKUSizeAvailabilityPrice Qty
D463729-25mg
25mg
In stock
$966.90
D463729-100mg
100mg
In stock
$3,478.90
D463729-500mg
500mg
In stock
$15,648.90
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Functional oligosaccharide Natural glycosides

Basic Description

SynonymsDioscin|19057-60-4|Collettiside III|Dioscine|CCRIS 4123|CHEBI:74023|UNII-3B95U4OLWV|3B95U4OLWV|PARIS III|(+)-DIOSCIN|(2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-ox
Specifications & PurityMoligand™, ≥95%(HPLC)
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
GradeMoligand™
Product Description

Dioscin is a natural steroid saponin derived from several plants, showing potent anti-cancer effect against a variety of tumor cell lines.

Description

Dioscin is a steroid saponin found in many varieties ofDiscorea.

Associated Targets

CXCR3 Tchem C-X-C chemokine receptor type 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFKBIA Tchem NF-kappa-B inhibitor alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SMAD2 Tbio Mothers against decapentaplegic homolog 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPK12 Tchem Mitogen-activated protein kinase 12 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MMP9 Tchem Matrix metalloproteinase-9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MMP2 Tchem 72 kDa type IV collagenase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
INCHI InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1
InChi Key VNONINPVFQTJOC-ZGXDEBHDSA-N
Canonical SMILES CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1
Isomeric SMILES C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)C)C)OC1
Alternate CAS 19057-60-4
PubChem CID 119245
MeSH Entry Terms dioscin
Molecular Weight 869.05

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
G2326621Certificate of AnalysisJul 07, 2023 D463729
G2326628Certificate of AnalysisJul 07, 2023 D463729
G2326689Certificate of AnalysisJul 07, 2023 D463729
G2326691Certificate of AnalysisJul 07, 2023 D463729
G2326707Certificate of AnalysisJul 07, 2023 D463729
G2326713Certificate of AnalysisJul 07, 2023 D463729

Chemical and Physical Properties

Sensitivitylight＆heat sensitive

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Dioscin - 10mM in DMSO, used for , CAS No. 19057-60-4(DMSO), by Aladdin Scientific
    Dioscin

    Starting at $1,581.90

  2. Dioscin - analytical standard,≥98%, used for , CAS No. 19057-60-4, by Aladdin Scientific
    Dioscin, Antagonist of CXCR3

    Starting at $441.90

References

1. Xufeng Tao, Lianhong Yin, Lina Xu, Jinyong Peng,.  (2018-10-14)  Dioscin: A diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections..  Pharmacological research,    ( 259-269 ).  [PMID:30315966]

Solution Calculators

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