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D106407-5g

Available within 4-8 weeks(?)

$29.90

D106407-25g

25g

Available within 4-8 weeks(?)

$86.90

D106407-100g

100g

Available within 4-8 weeks(?)

$311.90

Basic Description

Synonyms	Diphenyl diselenide\|1666-13-3\|Diselenide, diphenyl\|Phenyl diselenide\|1,2-Diphenyldiselane\|Diphenyldiselenide\|(phenyldiselanyl)benzene\|Bis(phenylselenide)\|diphenyldiselane\|9ATU3Z459Q\|CHEMBL3122204\|NSC-49763\|C12H10Se2\|CCRIS 9227\|EINECS 216-780-2\|MFCD0000300
Specifications & Purity	96%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Diphenyl diselenide (Ph2Se2) is an organoselenium compound. Its crystalline structure, toxicokinetic properties,antioxidant and anti-inflammatory activities have been investigated. Its ability to reverse the oxidative brain damage and mitochondrial dysfunction induced by acetaminophen has been studied in mice. It reacts with thallium (Tl) to form TI (SePh). It participates in a four-component radical coupling to form substituted cyclopentanes. Diphenyl diselenide inhibits δ-aminolevulinate dehydratase (δ-ALA-D) from brain, liver and kidney in vitro.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 1 Activities

Discover Target: EHMT2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EHMT1 Tchem Histone-lysine N-methyltransferase EHMT1 1 Activities

Discover Target: EHMT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(phenyldiselanyl)benzene
INCHI	InChI=1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H
InChi Key	YWWZCHLUQSHMCL-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)[Se][Se]C2=CC=CC=C2
Isomeric SMILES	C1=CC=C(C=C1)[Se][Se]C2=CC=CC=C2
WGK Germany	3
RTECS	JM9152500
PubChem CID	15460
UN Number	3283
Molecular Weight	312.13
Beilstein	2047179
Reaxy-Rn	2047179

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
L2004113	Certificate of Analysis	Sep 06, 2024	D106407
E2207020	Certificate of Analysis	Feb 17, 2022	D106407
E2207025	Certificate of Analysis	Feb 17, 2022	D106407
E2207030	Certificate of Analysis	Feb 17, 2022	D106407

Chemical and Physical Properties

Solubility	Insoluble in water, soluble in toluene
Sensitivity	Moisture &air sensitive
Boil Point(°C)	202°C/11mmHg
Melt Point(°C)	60-63°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS09
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H331:Toxic if inhaled H373:Causes damage to organs through prolonged or repeated exposure H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P391:Collect spillage. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	JM9152500
Reaxy-Rn	2047179

FAQs and Articles

FAQ

Ammonium peroxydisulfate

Categories: Technical articles

Tags:

Oxidizing agents Ammonium peroxydisulfate

References

1. E N Maciel,R C Bolzan,A L Braga,J B Rocha. (2000-11-18) Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice.. Journal of biochemical and molecular toxicology, 14 ((6)): (310-319). [PMID:11083084]
2. R M Rosa,R Roesler,A L Braga,J Saffi,J A P Henriques. (2008-06-24) Pharmacology and toxicology of diphenyl diselenide in several biological models.. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 40 ((10)): (1287-1304). [PMID:18572457]
3. D F Meinerz,M T de Paula,B Comparsi,M U Silva,A E Schmitz,H C Braga,P S Taube,A L Braga,J B T Rocha,A L Dafre,M Farina,J L Franco,T Posser. (2011-10-18) Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions.. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 44 ((11)): (1156-1163). [PMID:22002094]
4. Natalí L Chanaday,Andreza F de Bem,German A Roth. (2011-10-29) Effect of diphenyl diselenide on the development of experimental autoimmune encephalomyelitis.. Neurochemistry international, 59 ((8)): (1155-1162). [PMID:22032971]
5. Michele Hinerasky da Silva,Edovando José Flores da Rosa,Nélson Rodrigues de Carvalho,Fernando Dobrachinski,João Batista Teixeira da Rocha,Jose L Mauriz,Javier González-Gallego,Félix Alexandre Antunes Soares. (2011-11-15) Acute brain damage induced by acetaminophen in mice: effect of diphenyl diselenide on oxidative stress and mitochondrial dysfunction.. Neurotoxicity research, 21 ((3)): (334-344). [PMID:22081409]
6. Lucía L Rupil,Andreza F de Bem,German A Roth. (2012-01-05) Diphenyl diselenide-modulation of macrophage activation: down-regulation of classical and alternative activation markers.. Innate immunity, 18 ((4)): (627-637). [PMID:22215443]
7. Glaecir Roseni Mundstock Dias,Francielli Araújo Vieira,Fernando Dobrachinski,Jéssika Cristina Bridi,Rodrigo de Souza Balk,Félix Antunes Soares,Cristina Wayne Nogueira,Nilda Berenice de Vargas Barbosa. (2012-01-17) Diphenyl diselenide diet intake improves spatial learning and memory deficits in hypothyroid female rats.. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 30 ((2)): (83-89). [PMID:22244870]
8. Edovando J F da Rosa,Michele Hinerasky da Silva,Nelson Rodrigues Carvalho,Jessika Cristina Bridi,João Batista da Rocha,Sara Carbajo-Pescador,Jose Luiz Mauriz,Javier González-Gallego,Félix Alexandre Antunes Soares. (2012-02-04) Reduction of acute hepatic damage induced by acetaminophen after treatment with diphenyl diselenide in mice.. Toxicologic pathology, 40 ((4)): (605-613). [PMID:22301948]
9. César Augusto Brüning,Marina Prigol,Cristiane Luchese,Simone Pinton,Cristina Wayne Nogueira. (2012-03-31) Diphenyl diselenide ameliorates behavioral and oxidative parameters in an animal model of mania induced by ouabain.. Progress in neuro-psychopharmacology & biological psychiatry, 38 ((2)): (168-174). [PMID:22459096]
10. Carmine Inês Acker,Ana Cristina Guerra Souza,Maurício Portella Dos Santos,Cinthia Melazzo Mazzanti,Cristina Wayne Nogueira. (2012-04-06) Diphenyl diselenide attenuates hepatic and hematologic toxicity induced by chlorpyrifos acute exposure in rats.. Environmental science and pollution research international, 19 ((8)): (3481-3490). [PMID:22477165]
11. Charlene Cavalheiro de Menezes,Jossiele Leitemperger,Adriana Santi,Thais Lópes,Cátia Aline Veiverberg,Sandra Peixoto,Martha Bohrer Adaime,Renato Zanella,Nilda Berenice Vargas Barbosa,Vania Lucia Loro. (2012-05-23) The effects of diphenyl diselenide on oxidative stress biomarkers in Cyprinus carpio exposed to herbicide quinclorac (Facet®).. Ecotoxicology and environmental safety, 81 (91-97). [PMID:22608528]
12. Fernando Dobrachinski,Luiza Lena Bastos,Jessika Cristina Bridi,Cristiane Lenz Dalla Corte,Daiana Silva de Ávila,João Batista Teixeira da Rocha,Félix Alexandre Antunes Soares. (2012-06-08) Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid.. Neurochemical research, 37 ((9)): (1993-2003). [PMID:22674085]
13. Marina Prigol,César Augusto Brüning,Franciele Martini,Cristina W Nogueira. (2012-06-14) Comparative excretion and tissue distribution of selenium in mice and rats following treatment with diphenyl diselenide.. Biological trace element research, 150 ((1-3)): (272-277). [PMID:22692883]
14. Cristiane Luchese,Marina Prigol,Marta M M F Duarte,Cristina W Nogueira. (2012-06-16) Diphenyl diselenide reduces inflammation in the mouse model of pleurisy induced by carrageenan: reduction of pro-inflammatory markers and reactive species levels.. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 61 ((10)): (1117-1124). [PMID:22699806]
15. César A Brüning,Marina Prigol,Cristiane Luchese,Cristiano R Jesse,Marta M M F Duarte,Silvane S Roman,Cristina W Nogueira. (2012-08-01) Protective effect of diphenyl diselenide on ischemia and reperfusion-induced cerebral injury: involvement of oxidative stress and pro-inflammatory cytokines.. Neurochemical research, 37 ((10)): (2249-2258). [PMID:22846969]
16. Abhijit Sau,Anup Kumar Misra. (2012-09-18) Reaction of glycal derivatives with alcohols in the presence of N-bromosuccinimide and diphenyldiselenide: preparation of 2-deoxy-2-phenylselenyl glycosides.. Carbohydrate research, 361 (41-48). [PMID:22982170]
17. Mohammad Ibrahim,Waseem Hassan,Daiane Francine Meinerz,Matheus Dos Santos,Claudia V Klimaczewski,Anna M Deobald,Maricilia S Costa,Cristina W Nogueira,Nilda B V Barbosa,Joao B T Rocha. (2012-09-18) Antioxidant properties of diorganoyl diselenides and ditellurides: modulation by organic aryl or naphthyl moiety.. Molecular and cellular biochemistry, 371 ((1-2)): (97-104). [PMID:22983825]
18. Marina Prigol,Cristina W Nogueira,Gilson Zeni,Maria Rosário Bronze,Luís Constantino. (2012-10-02) In vitro metabolism of diphenyl diselenide in rat liver fractions. Conjugation with GSH and binding to thiol groups.. Chemico-biological interactions, 200 ((2-3)): (65-72). [PMID:23022272]
19. Juliana Trevisan da Rocha,Tuane Bazanella Sampaio,José S Santos Neto,Cristina Wayne Nogueira,Gilson Zeni. (2012-10-23) Cognitive effects of diphenyl diselenide and estradiol treatments in ovariectomized mice.. Neurobiology of learning and memory, 99 (17-24). [PMID:23085182]
20. Waseem Hassan,Joao Batista Teixeira Rocha. (2012-10-23) Interaction profile of diphenyl diselenide with pharmacologically significant thiols.. Molecules (Basel, Switzerland), 17 ((10)): (12287-12296). [PMID:23085664]
21. Marina Prigol,Cristina W Nogueira,Gilson Zeni,Maria Rosário Bronze,Luís Constantino. (2013-01-08) Physicochemical and biochemical profiling of diphenyl diselenide.. Applied biochemistry and biotechnology, 169 ((3)): (885-893). [PMID:23292905]
22. Charlene Menezes,Jossiele Leitemperger,Cândida Toni,Adriana Santi,Thais Lópes,Nilda Berenice Vargas Barbosa,João Radünz Neto,Vania Lucia Loro. (2013-07-31) Comparative study on effects of dietary with diphenyl diselenide on oxidative stress in carp (Cyprinus carpio) and silver catfish (Rhamdia sp.) exposed to herbicide clomazone.. Environmental toxicology and pharmacology, 36 ((2)): (706-714). [PMID:23892285]
23. Fernando Dobrachinski,Michele Hinerasky da Silva,Cíntia Letícia Cardias Tassi,Nélson Rodrigues de Carvalho,Glaecir Roseni Mundstock Dias,Ronaldo Medeiros Golombieski,Elgion Lúcio da Silva Loreto,João Batista Teixeira da Rocha,Michele Rechia Fighera,Félix Alexandre Antunes Soares. (2014-03-13) Neuroprotective effect of diphenyl diselenide in a experimental stroke model: maintenance of redox system in mitochondria of brain regions.. Neurotoxicity research, 26 ((4)): (317-330). [PMID:24615369]
24. Cleber F Barbosa,Alexandre A Tonin,Aleksandro S Da Silva,Maria I De Azevedo,Danieli U Monteiro,Emily P Waczuk,Thiago Duarte,Carine Hermes,Giovana Camillo,Fernanda F Vogel,Luciana Faccio,Paula T Tonin,Patricia Wolkmer,Marta R Leal,Marta M M F Duarte,Rafael N Moresco,Sonia T A Lopes,Mario L De La Rue. (2014-08-12) Diphenyl diselenide and sodium selenite associated with chemotherapy in experimental toxoplasmosis: influence on oxidant/antioxidant biomarkers and cytokine modulation.. Parasitology, 141 ((13)): (1761-1768). [PMID:25111395]
25. Caitlyn M Gatley,Lisa M Muller,Meredith A Lang,Eduardo E Alberto,Michael R Detty. (2015-05-29) Xerogel-sequestered silanated organochalcogenide catalysts for bromination with hydrogen peroxide and sodium bromide.. Molecules (Basel, Switzerland), 20 ((6)): (9616-9639). [PMID:26016550]
26. Xing Wang,Yi Huan,Caina Li,Hui Cao,Sujuan Sun,Lei Lei,Quan Liu,Shuainan Liu,Wenming Ji,Hongmei Liu,Kaixun Huang,Jun Zhou,Zhufang Shen. (2020-09-20) Diphenyl diselenide alleviates diabetic peripheral neuropathy in rats with streptozotocin-induced diabetes by modulating oxidative stress.. Biochemical pharmacology, 182 (114221-114221). [PMID:32949583]
27. Pengshang Zhou,Gearoid Collins,Zeger Hens,Kevin M Ryan,Hugh Geaney,Shalini Singh. (2020-11-05) Colloidal WSe2 nanocrystals as anodes for lithium-ion batteries.. Nanoscale, 12 ((43)): (22307-22316). [PMID:33146655]
28. Yunhee Cho,Thi Anh Le,Hyunjung Kim,Yeseul Hong,Heemin Hwang,G Hwan Park,Sohyeon Seo,Hyoyoung Lee. (2021-01-08) Unveiling surface charge on chalcogen atoms toward the high aspect-ratio colloidal growth of two-dimensional transition metal chalcogenides.. Nanoscale, 13 ((2)): (1291-1302). [PMID:33409525]
29. Erico Silva Loreto,Sydney Hartz Alves,Janio Morais Santurio,Cristina Wayne Nogueira,Gilson Zeni. (2011-11-08) Diphenyl diselenide in vitro and in vivo activity against the oomycete Pythium insidiosum.. Veterinary microbiology, 156 ((1-2)): (222-226). [PMID:22055205]
30. Cristiane L Dalla Corte,Luíza L Bastos,Fernando Dobrachinski,João B T Rocha,Félix A A Soares. (2011-12-03) The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.. Brain research, 1430 (101-111). [PMID:22133308]
31. Juliana T da Rocha,Simone Pinton,Alexandre Mazzanti,Cinthia M Mazzanti,Diego V Beckemann,Cristina W Nogueira,Gilson Zeni. (2011-12-06) Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats.. Behavioural pharmacology, 23 ((1)): (98-104). [PMID:22139607]
32. Claire M Weekley,Jade B Aitken,Ian F Musgrave,Hugh H Harris. (2012-01-17) Methylselenocysteine treatment leads to diselenide formation in human cancer cells: evidence from X-ray absorption spectroscopy studies.. Biochemistry, 51 ((3)): (736-738). [PMID:22242710]
33. Juliana Trevisan da Rocha,Bibiana Mozzaquatro Gai,Simone Pinton,Tuane Bazanella Sampaio,Cristina Wayne Nogueira,Gilson Zeni. (2012-03-28) Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system.. Psychopharmacology, 222 ((4)): (709-719). [PMID:22451092]
34. Viviane Glaser,Bettina Moritz,Ariana Schmitz,Alcir Luiz Dafré,Evelise Maria Nazari,Yara Maria Rauh Müller,Luciane Feksa,Marcos Raniel Straliottoa,Andreza Fabro de Bem,Marcelo Farina,João Batista Teixeira da Rocha,Alexandra Latini. (2013-08-21) Protective effects of diphenyl diselenide in a mouse model of brain toxicity.. Chemico-biological interactions, 206 ((1)): (18-26). [PMID:23954720]
35. Desirée Bartolini,Yanzhong Wang,Jie Zhang,Daniela Giustarini,Ranieri Rossi,Gavin Y Wang,Pierangelo Torquato,Danyelle M Townsend,Kenneth D Tew,Francesco Galli. (2019-04-30) A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities.. PloS one, 14 ((4)): (e0205626-e0205626). [PMID:31034521]

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Diphenyl diselenide - 96%, high purity , CAS No.1666-13-3

Basic Description

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 1 Activities

EHMT1 Tchem Histone-lysine N-methyltransferase EHMT1 1 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

FAQs and Articles

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
D106407-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$29.90
D106407-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$86.90
D106407-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$311.90