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Disopyramide - 98%, high purity , CAS No.3737-09-5, Channel blocker of K v11.1
Basic Description Synonyms disopyramide|3737-09-5|Dicorantil|Isorythm|Ritmodan|Lispine|Disopiramida|Rythmodan|Rythmodan P|Searle 703|Disopyramidum|Ritmilen|Disopyramidum [INN-Latin]|Dl-disopyramide|Disopiramida [INN-Spanish]|SC 7031|Disopyramide Free Base|(rs)-disopyramide|SC-7031| Specifications & Purity Moligand™, ≥98% Shipped In Normal Grade Moligand™ Action Type CHANNEL BLOCKER Mechanism of action Channel blocker of K v11.1 Product Description Disopyramide (Dicorantil) is a class IA antiarrhythmic drug with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action
Names and Identifiers IUPAC Name 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide INCHI InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25) InChi Key UVTNFZQICZKOEM-UHFFFAOYSA-N Canonical SMILES CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C Isomeric SMILES CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C WGK Germany 3 PubChem CID 3114 Molecular Weight 339.47
Chemical and Physical Properties Solubility Slightly soluble in water Melt Point(°C) 96°C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
WGK Germany 3 Merck Index 3360
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G2226445