Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Synonyms | Solketal|100-79-8|2,2-Dimethyl-1,3-dioxolane-4-methanol|(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol|Isopropylidene glycerol|Glycerolacetone|DL-1,2-Isopropylideneglycerol|Glycerol dimethylketal|1,2-Isopropylideneglycerol|1,3-Dioxolane-4-methanol, 2,2-dimethyl |
|---|---|
| Specifications & Purity | ≥98%, mixture of isomer |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Product Description | DL-1,2-Isopropylideneglycerol undergoes effective isopropylidenation and deprotection reaction catalyzed by phosphotungstic acid |
Names and Identifiers
| Pubchem Sid | 488180474 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488180474 |
| IUPAC Name | (2,2-dimethyl-1,3-dioxolan-4-yl)methanol |
| INCHI | InChI=1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3 |
| InChi Key | RNVYQYLELCKWAN-UHFFFAOYSA-N |
| Canonical SMILES | CC1(OCC(O1)CO)C |
| Isomeric SMILES | CC1(OCC(O1)CO)C |
| WGK Germany | 2 |
| RTECS | JI0400000 |
| PubChem CID | 7528 |
| Molecular Weight | 132.16 |
| Beilstein | 104465 |
| Reaxy-Rn | 104465 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L2007090 | Certificate of Analysis | Sep 06, 2024 | D102242 |
| E2421142 | Certificate of Analysis | Apr 30, 2024 | D102242 |
| E2421143 | Certificate of Analysis | Apr 30, 2024 | D102242 |
| A2419284 | Certificate of Analysis | Jan 05, 2024 | D102242 |
| A2412288 | Certificate of Analysis | Dec 28, 2023 | D102242 |
| A2412289 | Certificate of Analysis | Dec 28, 2023 | D102242 |
| A2412290 | Certificate of Analysis | Dec 28, 2023 | D102242 |
| A2412291 | Certificate of Analysis | Dec 28, 2023 | D102242 |
| G1918086 | Certificate of Analysis | May 08, 2023 | D102242 |
| G2304713 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304712 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304711 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304601 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304654 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304655 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304710 | Certificate of Analysis | Jan 04, 2023 | D102242 |
| G2304656 | Certificate of Analysis | Dec 13, 2022 | D102242 |
| L2216836 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| K2228279 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| G2214213 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| G2214212 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| G2214211 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| G2214208 | Certificate of Analysis | Jun 25, 2022 | D102242 |
| B2223112 | Certificate of Analysis | Feb 26, 2022 | D102242 |
| A2218058 | Certificate of Analysis | Feb 21, 2022 | D102242 |
more
Chemical and Physical Properties
| Solubility | Soluble in water (fully), alcohol, acetals, esters, and ethers. |
|---|---|
| Sensitivity | Air sensitive |
| Refractive Index | 1.434 |
| Flash Point(°F) | 194 °F |
| Flash Point(°C) | 80°C |
| Boil Point(°C) | 188-189°C |
| Melt Point(°C) | -27°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS09, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
| WGK Germany | 2 |
| RTECS | JI0400000 |
| Reaxy-Rn | 104465 |
| Merck Index | 5213 |
Related Documents
References
| 1. S L Cheav,R Chahine,A F Prigent. (1992-11-01) Effects of glycerol acetonide on adrenergic neurotransmission in isolated rabbit heart.. Arzneimittel-Forschung, 42 ((11)): (1288-1291). [PMID:1337247] |
| 2. S L Cheav,F F Ziade,O Foussard-Blanpin. (1987-01-01) [Interference of the action of dimethyl-2,2-hydroxymethyl-4 dioxolane- 1,3 (AG) with various active pharmacomolecules on the central nervous system].. Annales pharmaceutiques francaises, 45 ((6)): (445-451). [PMID:3504119] |
| 3. D R Kodali. (1987-04-01) Improved method for the synthesis of 1- or 3-acyl-sn-glycerols.. Journal of lipid research, 28 ((4)): (464-469). [PMID:3585180] |
| 4. S L Cheav,F F Ziade,O Foussard-Blanpin. (1986-01-01) [Change in behavior of mice and rats under the effect of dimethyl-2,2 hydroxymethyl-4 dioxolanne-1,3 (glycerol acetonide)].. Annales pharmaceutiques francaises, 44 ((6)): (487-494). [PMID:3619328] |
| 5. H Suemune,Y Mizuhara,H Akita,K Sakai. (1986-08-01) Enzymatic synthesis of 2,3-O-isopropylidene-sn-glycerol, a chiral building block for platelet-activating factor.. Chemical & pharmaceutical bulletin, 34 ((8)): (3440-3444). [PMID:3791517] |
| 6. P Kanda,M A Wells. (1981-07-01) Synthesis of sn-glycero-1-phosphocholine.. Journal of lipid research, 22 ((5)): (879-882). [PMID:7288295] |
| 7. P Kanda,M A Wells. (1980-02-01) A simplified procedure for the preparation of 2,3-O-isopropylidene-sn-glycerol from L-arabinose.. Journal of lipid research, 21 ((2)): (257-258). [PMID:7373164] |
| 8. K T Geiss,J M Frazier. (2001-07-17) In vitro toxicities of experimental jet fuel system ice-inhibiting agents.. The Science of the total environment, 274 ((1-3)): (209-218). [PMID:11453297] |
| 9. Aldo Jongejan,Jaap A Jongejan,Wilfred R Hagen. (2003-04-11) Deuterium isotope effect on enantioselectivity in the Comamonas testosteroni quinohemoprotein alcohol dehydrogenase-catalyzed kinetic resolution of rac-2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane, solketal.. Biochimica et biophysica acta, 1647 ((1-2)): (297-302). [PMID:12686148] |
| 10. Xiaolin Cao,Rekha D Shah,Rina K Dukor,Changning Guo,Teresa B Freedman,Laurence A Nafie. (2004-10-14) Extension of fourier transform vibrational circular dichroism into the near-infrared region: continuous spectral coverage from 800 to 10 000 cm(-1).. Applied spectroscopy, 58 ((9)): (1057-1064). [PMID:15479522] |
| 11. Changning Guo,Rekha D Shah,John Mills,Rina K Dukor,Xiaolin Cao,Teresa B Freedman,Laurence A Nafie. (2006-08-15) Fourier transform near-infrared vibrational circular dichroism used for on-line monitoring the epimerization of 2,2-dimethyl-1,3-dioxolane-4-methanol: A pseudo racemization reaction.. Chirality, 18 ((10)): (775-782). [PMID:16906494] |
| 12. John H Grabber,Paul F Schatz,Hoon Kim,Fachuang Lu,John Ralph. (2010-06-23) Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability.. BMC plant biology, 10 (114-114). [PMID:20565789] |
| 13. Thomas Mendgen,Therese Scholz,Christian D Klein. (2010-08-24) Structure-activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA.. Bioorganic & medicinal chemistry letters, 20 ((19)): (5757-5762). [PMID:20729083] |
| 14. Naoshi Kojima,Yasuo Komatsu. (2012-03-08) Synthesis and application of highly reactive amino linkers for functional oligonucleotides.. Current protocols in nucleic acid chemistry, Chapter 4 (Unit 4-Unit 4). [PMID:22395967] |
| 15. Manoj K Gupta,Zhexi Li,Timothy S Snowden. (2012-05-09) One-pot synthesis of trichloromethyl carbinols from primary alcohols.. The Journal of organic chemistry, 77 ((10)): (4854-4860). [PMID:22559051] |
| 16. Alvise Perosa,Andrea Moraschini,Maurizio Selva,Marco Noè. (2016-02-04) Synthesis of the Fatty Esters of Solketal and Glycerol-Formal: Biobased Specialty Chemicals.. Molecules (Basel, Switzerland), 21 ((2)): (170-170). [PMID:26840287] |
| 17. Renjie Liu,Dharmesh Patel,Hazel R C Screen,C Remzi Becer. (2017-06-22) A. Bioconjugate chemistry, 28 ((7)): (1955-1964). [PMID:28636335] |