| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| D647214-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $250.90 |
Alkaloids Isoquinoline Alkaloids
| Synonyms | Laudanosine|DL-Laudanosine|1699-51-0|1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline|(R,S)-Laudanosine|Laudanosine (R,S)|5',8-Dimethoxylaudanosine hydrochloride|1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihyd |
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| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity. |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity. In Vivo DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male CFLP mice weighing 18-25 g, and male Wistar rats weighing 120-150 g. Dosage: 10-20 mg/kg. Administration: IV. Result: Caused convulsions and hind limb extensions. Form:Solid |
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| IUPAC Name | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline |
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| INCHI | InChI=1S/C21H27NO4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17H,8-10H2,1-5H3 |
| InChi Key | KGPAYJZAMGEDIQ-UHFFFAOYSA-N |
| Canonical SMILES | CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC |
| Isomeric SMILES | CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC |
| PubChem CID | 15548 |
| Molecular Weight | 357.44 |
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| Solubility | DMSO : 100 mg/mL (279.77 mM; Need ultrasonic) |
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| Pictogram(s) | GHS06 |
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| Signal | Danger |
| Hazard Statements | H301:Toxic if swallowed H311:Toxic in contact with skin H331:Toxic if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. |
