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DL-Menthol - 98%, high purity , CAS No.89-78-1, Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3

  • Moligand™
  • ≥98%
Item Number
M105138
Grouped product items
SKUSizeAvailabilityPrice Qty
M105138-5ml
5ml
In stock
$27.90
M105138-25ml
25ml
In stock
$52.90
M105138-100ml
100ml
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$130.90
M105138-500ml
500ml
In stock
$587.90
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Alcohol C10-C11 Monocyclic monoterpenes Terpenoids TRPA1 Activator TRPA1 Gating inhibitor TRPM8 Activator TRPV3 Activator

Basic Description

SynonymsMENTHOL|dl-Menthol|1490-04-6|2-Isopropyl-5-methylcyclohexanol|15356-70-4|Cyclohexanol, 5-methyl-2-(1-methylethyl)-|89-78-1|Menthyl alcohol|p-Menthan-3-ol|Mentholum|Caswell No. 540|Mineral ice|Hexahydrothymol|5-Methyl-2-(1-methylethyl)cyclohexanol|3-Hydrox
Specifications & PurityMoligand™, ≥98%
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeACTIVATOR, GATING INHIBITOR
Mechanism of actionActivator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3
Product Description

DL-Menthol triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. The (-)-Menthol form exists naturally in nature, primarily found in fruit extracts or spearmint extracts. This racemic mixture could theoretically be created by the hydrogenation of the monoterpene pulegone.
A chemical which triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro.

Associated Targets

RUNX1 Tbio Runt-related transcription factor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT2B7 Tchem UDP-glucuronosyltransferase 2B7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT2B15 Tbio UDP-glucuronosyltransferase 2B15 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A9 Tbio UDP-glucuronosyltransferase 1-9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR1H4 Tclin Bile acid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPM8 Tclin Transient receptor potential cation channel subfamily M member 8 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A3 Tbio UDP-glucuronosyltransferase 1-3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

UGT1A6 Tbio UDP-glucuronosyltransferase 1-6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488179611
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179611
IUPAC Name 5-methyl-2-propan-2-ylcyclohexan-1-ol
INCHI InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
InChi Key NOOLISFMXDJSKH-UHFFFAOYSA-N
Canonical SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O
Isomeric SMILES CC1CCC(C(C1)O)C(C)C
WGK Germany 2
RTECS OT0350000
Alternate CAS 15356-70-4;1490-04-6
PubChem CID 1254
Molecular Weight 156.27
Beilstein 3194263
Reaxy-Rn 1902288

Certificates

Certificate of Analysis(COA)

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19 results found

Lot NumberCertificate TypeDateItem
C2430096Certificate of AnalysisMar 11, 2024 M105138
C2430097Certificate of AnalysisMar 11, 2024 M105138
C2430098Certificate of AnalysisMar 11, 2024 M105138
C2430099Certificate of AnalysisMar 11, 2024 M105138
C2408479Certificate of AnalysisFeb 28, 2024 M105138
F2303576Certificate of AnalysisMay 17, 2023 M105138
F2303533Certificate of AnalysisMay 17, 2023 M105138
F2303480Certificate of AnalysisMay 17, 2023 M105138
F2303479Certificate of AnalysisMay 17, 2023 M105138
F2303459Certificate of AnalysisMay 17, 2023 M105138
F2303475Certificate of AnalysisMay 17, 2023 M105138
B2318027Certificate of AnalysisJan 10, 2023 M105138
B2318035Certificate of AnalysisJan 10, 2023 M105138
B2318033Certificate of AnalysisJan 10, 2023 M105138
B2318032Certificate of AnalysisJan 10, 2023 M105138
B23171137Certificate of AnalysisJan 10, 2023 M105138
G2216358Certificate of AnalysisJun 25, 2022 M105138
G2216359Certificate of AnalysisJun 25, 2022 M105138
G2218008Certificate of AnalysisJun 25, 2022 M105138

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Chemical and Physical Properties

SolubilitySoluble in water (partly), and alcohol.
SensitivityHeat Sensitive
Flash Point(°F)199.4 °F
Flash Point(°C)93 °C
Boil Point(°C)216°C
Melt Point(°C)32-36°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 2
RTECS OT0350000
Reaxy-Rn 1902288

Related Documents

 SDS

 Specification Sheet

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  15. (1R,2S,5R)-(-)-Menthol - Standard for GC ,≥99.5%(GC), used for , CAS No. 2216-51-5, by Aladdin Scientific
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References

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