| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| D420534-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Non-specific free radical scavenger. Anti-oxidant.
| Synonyms | thioctic acid|dl-Thioctic acid|1077-28-7|alpha-Lipoic acid|5-(1,2-Dithiolan-3-yl)pentanoic acid|1,2-dithiolane-3-pentanoic acid|DL-alpha-Lipoic acid|alpha Lipoic Acid|Biletan|62-46-4|6,8-Thioctic acid|Thioctacid|DL-6,8-Thioctic acid|dl-Lipoic acid|6-Thioc |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Dry ice |
| Product Description | α-Lipoic acid (LA), a nutritional component found in vegetables and meat, has both antioxidant and oxidant properties. LA exerts therapeutic potential to many diseases like liver cirrhosis, heavy metal poisoning, and diabetic polyneuropathy. LA exerts apoptotic potential in cancer cells either by oxidative stress related pathway or by activation of caspases. DL-Thioctic acid acid has been used in in vitro lipoylation studies and in the pyruvate dehydrogenase complex (PDC)-pyruvate dehydrogenase kinase (PDHK) functional assay.It has also been used to investigate its antioxidative effect on developing cerebellum of rats exposed to arsenic during postnatal period; DL-Thioctic acid can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats. It has also been used to analyze ROS production in astrocytes |
| IUPAC Name | 5-(dithiolan-3-yl)pentanoic acid |
|---|---|
| INCHI | InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) |
| InChi Key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
| Canonical SMILES | C1CSSC1CCCCC(=O)O |
| Isomeric SMILES | C1CSSC1CCCCC(=O)O |
| WGK Germany | 3 |
| RTECS | JP1192000 |
| PubChem CID | 864 |
| Molecular Weight | 206.33 |
| Beilstein | 81853 |
| Reaxy-Rn | 81851 |
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| Sensitivity | Air & Moisture & Heat & Light Sensitive |
|---|---|
| Boil Point(°C) | 160-165℃ |
| Melt Point(°C) | 62°C |
| Pictogram(s) | GHS09, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H302:Harmful if swallowed H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
| WGK Germany | 3 |
| RTECS | JP1192000 |
| Reaxy-Rn | 81851 |
| Merck Index | 9326 |
