DM3 - 95%, high purity , CAS No.796073-54-6

  • ≥95%
Item Number
D647541
Grouped product items
SKUSizeAvailabilityPrice Qty
D647541-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$710.90
D647541-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,200.90

Basic Description

SynonymsHY-130080 | XNG6QZ89ZB | N(2')-Deacetyl-N2-(4-mercapto-4-methyl-1-oxopentyl)-maytansine | SCHEMBL18757725 | Maytansinoid DM3 | DM3 | Maytansine, N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)- | CS-0104939 | Maytansinoid DM 3 | UNII-XNG6QZ89ZB
Specifications & Purity≥95%
Biochemical and Physiological MechanismsDM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)

Form:Solid

IC50& Target:Maytansinoids

Names and Identifiers

IUPAC Name [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(4-sulfanylpentanoyl)amino]propanoate
INCHI InChI=1S/C37H52ClN3O10S/c1-20-11-10-12-28(48-9)37(46)19-27(49-35(45)39-37)22(3)33-36(5,51-33)29(50-34(44)23(4)40(6)30(42)14-13-21(2)52)18-31(43)41(7)25-16-24(15-20)17-26(47-8)32(25)38/h10-12,16-17,21-23,27-29,33,46,52H,13-15,18-19H2,1-9H3,(H,39,45)/b12-10+,20-11+/t21?,22-,23+,27+,28-,29+,33+,36+,37+/m1/s1
InChi Key LJFFDOBFKICLHN-IXWHRVGISA-N
Canonical SMILES CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCC(C)S)C)C)OC)(NC(=O)O2)O
Isomeric SMILES C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)C)\C)OC)(NC(=O)O2)O
Alternate CAS 796073-54-6
PubChem CID 11578612
Molecular Weight 766.34

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (130.49 mM; ultrasonic and warming and heat to 60°C)

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Solution Calculators