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DOCK2-IN-1 - 96%, high purity , CAS No.4590-86-7

Item Number

D649859

Grouped product items
SKU	Size	Availability	Price	Qty
D649859-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$260.90
D649859-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$380.90

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Basic Description

Specifications & Purity	96%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	DOCK2-IN-1 (compound 3), a CPYPP ( HY-110100 ) analogue, is an inhibitor of DOCK2 as well ( IC 50 =19.1 μM). DOCK2-IN-1 binds to DOCK2 DHR-2 domain in a reversible manner to inhibits its catalytic activity. DOCK2-IN-1 blocks the activation of both chemokine receptor- and antigen receptor-mediated Rac in lymphocytes. DOCK2-IN-1 significantly suppresses chemotactic response and T cell activation Form:Solid IC50& Target:DOCK2

Canonical SMILES	O=C1NN(C(/C1=C/C2=C(Cl)C=CC=C2)=O)C3=CC=CC=C3
Molecular Weight	298.72

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Solubility	DMSO : 125 mg/mL (418.45 mM; Need ultrasonic)

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