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Donepezil-d5 - ≥99.0%, high purity , CAS No.1128086-25-8

  • ≥99%
Item Number
D646623
Grouped product items
SKUSizeAvailabilityPrice Qty
D646623-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$950.90

Basic Description

Specifications & Purity≥99.0%
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Donepezil-d 5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE , respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

Canonical SMILES O=C1C2=CC(OC)=C(OC)C=C2CC1CC3CCN(CC3)CC4=C([2H])C([2H])=C([2H])C([2H])=C4[2H]
Molecular Weight 384.52

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