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Doramectin - 98%, high purity , CAS No.117704-25-3

≥98%

CAS#: 117704-25-3
Formula: C₅₀H₇₄O₁₄
Molecular Weight: 899.11
MDL number: MFCD00894747
PubChem CID: 9832750

Item Number

D127678

Grouped product items
SKU	Size	Availability	Price
D127678-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$9.90
D127678-1g	1g	In stock	$20.90
D127678-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$70.90

View related series

Anti-infection Antibiotic Bacterial Parasite

Basic Description

Synonyms	Doramectin\|117704-25-3\|Dectomax\|Doramectina\|Doramectine\|Doramectinum\|UK 67994\|UK-67,994\|UNII-KGD7A54H5P\|KGD7A54H5P\|DTXSID9048982\|UK-67994\|HSDB 7452\|Doramectine [INN-French]\|Doramectinum [INN-Latin]\|Doramectina [INN-Spanish]\|NSC-760342\|L-701023\|DTXCID50289
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Doramectin is a derivative of ivermectin. It is thought to work like other macrocyclic lactones by opening glutamate-gated chloride channels in the nerve cells, causing paralysis.
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice
Product Description	Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
INCHI	InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1
InChi Key	QLFZZSKTJWDQOS-YDBLARSUSA-N
Canonical SMILES	CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)C=CC(C(O7)C8CCCCC8)C)O
Isomeric SMILES	C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C8CCCCC8)C)O
WGK Germany	3
PubChem CID	9832750
Molecular Weight	899.11

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
G2429426	Certificate of Analysis	Jul 10, 2024	D127678
G2429429	Certificate of Analysis	Jul 10, 2024	D127678
G2429431	Certificate of Analysis	Jul 10, 2024	D127678
G2429434	Certificate of Analysis	Jul 10, 2024	D127678
E1504009	Certificate of Analysis	Dec 06, 2022	D127678

Solubility

Soluble in water (partly), chloroform, and methanol., Soluble in water (partly), chloroform, and methanol.

Sensitivity

Heat sensitive; light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS09, GHS07
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H302:Harmful if swallowed H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H300:Fatal if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H370:Causes damage to organs H361:Suspected of damaging fertility or the unborn child H362:May cause harm to breast-fed children
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3

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