DOTAP Transfection Reagent - 1 mg/ml in MES-buffered saline, high purity , CAS No.144189-73-1

Item Number

D353304

Grouped product items
SKU	Size	Availability	Price	Qty
D353304-400μl	400μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$156.90

a cationic lipid formulation used for transfection of DNA, RNA, and YAC.

Basic Description

Synonyms	CS-0185615 \| DOTAP \| 18:1 TAP (DOTAP, MS Salt), 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt), chloroform \| N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate \| DOTAP Liposomal Transfection Reagent, N-[1-(2,3-Dioleoyloxy)pr
Specifications & Purity	1 mg/ml in MES-buffered saline
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	DOTAP Transfection Reagent is a liposomal formulation of the cationic lipid DOTAP. DOTAP Transfection Reagent is used not only for DNA and RNA transfection, but yeast artificial chromosomes (YAC) as well, with or without serum. This transfection via DOTAP Transfection Reagent is between eukaryotic cells in iehter transient or stable gene expression. DOTAP Transfection Reagent is also suitable for other negatively charged molecules, including oligonucleotidees and glutamic acid.

Names and Identifiers

IUPAC Name	2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl-trimethylazanium;methyl sulfate
INCHI	InChI=1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
InChi Key	RSMRWWHFJMENJH-LQDDAWAPSA-M
Canonical SMILES	CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.COS(=O)(=O)[O-]
Isomeric SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC.COS(=O)(=O)[O-]
WGK Germany	3
PubChem CID	16218742
Molecular Weight	774.19

Citations of This Product

1. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu. (2022) A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma. Biomaterials Science, 10 (23): (6791-6803). [PMID:36314541] [10.1039/D2BM01145J]

References

1. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu. (2022) A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma. Biomaterials Science, 10 (23): (6791-6803). [PMID:36314541] [10.1039/D2BM01145J]

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Basic Description