DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC 50 of 10 μM
In Vitro
DSHS00884 stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC 50 of 2.5-25 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.