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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D609991-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $139.90 | |
D609991-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,400.90 | |
D609991-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $639.90 | |
D609991-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,279.90 |
Specifications & Purity | ≥98% |
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Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Mechanism of action | Plasmodium falciparum dihydroorotate dehydrogenase |
Product Description |
DSM502 is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. DSM502 exhibits nanomolar potency againsts Plasmodium DHODH and Plasmodium parasites, with no inhibition of mammalian DHODHs
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Canonical SMILES | O=C(C1=C(C)C(CC2=CC=C(C(F)(F)F)N=C2)=CN1)NC3CC3 |
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Molecular Weight | 323.31 |
PubChem CID | 154699462 |
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ChEMBL Ligand | CHEMBL4633246 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
H2420200 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420201 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420202 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420203 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420204 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420205 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420206 | Certificate of Analysis | May 08, 2024 | D609991 |
H2420215 | Certificate of Analysis | May 08, 2024 | D609991 |
1. Kokkonda S, Deng X, White KL, El Mazouni F, White J, Shackleford DM, Katneni K, Chiu FCK, Barker H, McLaren J et al.. (2020) Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.. J Med Chem, 63 (9): (4929-4956). [PMID:32248693] |