DX-9065a , CAS No.155204-81-2, Inhibitor of coagulation factor X

Item Number

D610027

Grouped product items
SKU	Size	Availability	Price	Qty
D610027-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D610027-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	RF60GS0DRO\|UNII-RF60GS0DRO\|150612-55-8\|DX-9065\|CHEMBL19902\|(2s)-3-(7-Carbamimidoylnaphthalen-2-Yl)-2-[4-({(3r)-1-[(1z)-Ethanimidoyl]pyrrolidin-3-Yl}oxy)phenyl]propanoic Acid\|CHEMBL539053\|1fax\|(alphaS)-7-(Aminoiminomethyl)-alpha-(4-(((3S)-1-(1-iminoethyl)-
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of coagulation factor X

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PubChem CID

CAS Registry No.

ChEMBL Ligand

RCSB PDB Ligand

References

1. Kaiser B. (2003) DX-9065a, a direct inhibitor of factor Xa.. Cardiovasc Drug Rev, 21 (2): (91-104). [PMID:12847561]
2. Ieko M, Tarumi T, Takeda M, Naito S, Nakabayashi T, Koike T. (2004) Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis.. J Thromb Haemost, 2 (4): (612-8). [PMID:15102016]
3. Hara T, Yokoyama A, Ishihara H, Yokoyama Y, Nagahara T, Iwamoto M. (1994) DX-9065a, a new synthetic, potent anticoagulant and selective inhibitor for factor Xa.. Thromb Haemost, 71 (3): (314-9). [PMID:8029795]
4. Nagahara T, Yokoyama Y, Inamura K, Katakura S, Komoriya S, Yamaguchi H, Hara T, Iwamoto M. (1994) Dibasic (amidinoaryl)propanoic acid derivatives as novel blood coagulation factor Xa inhibitors.. J Med Chem, 37 (8): (1200-7). [PMID:8164262]

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Basic Description