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EB-42486 , CAS No.E610050, Inhibitor of leucine rich repeat kinase 2

Item Number

E610050

Grouped product items
SKU	Size	Availability	Price	Qty
E610050-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
E610050-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 31
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of leucine rich repeat kinase 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C22H22N8O/c1-13-18(22(2,3)30-21(29(13)4)26-27-28-30)20(31)23-15-10-11-17-16(12-15)19(25-24-17)14-8-6-5-7-9-14/h5-12H,1-4H3,(H,23,31)(H,24,25)
InChi Key	KHSAHYKLUPESPP-UHFFFAOYSA-N
Canonical SMILES	O=C(C1=C(C)N(C)c2n(C1(C)C)nnn2)Nc1ccc2c(c1)c(n[nH]2)c1ccccc1
PubChem CID	155925851

PubChem CID	155925851

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1. Garofalo AW, Bright J, De Lombaert S, Toda AMA, Zobel K, Andreotti D, Beato C, Bernardi S, Budassi F, Caberlotto L et al.. (2020) Selective Inhibitors of G2019S-LRRK2 Kinase Activity.. J Med Chem, 63 (23): (14821-14839). [PMID:33197196]

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